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排序方式: 共有237条查询结果,搜索用时 15 毫秒
1.
Casey Crump Kenny Crump Eric Hack Rose Luippold Kenneth Mundt Elizabeth Liebig Julie Panko Dennis Paustenbach Deborah Proctor 《Risk analysis》2003,23(6):1147-1163
This study evaluates the dose-response relationship for inhalation exposure to hexavalent chromium [Cr(VI)] and lung cancer mortality for workers of a chromate production facility, and provides estimates of the carcinogenic potency. The data were analyzed using relative risk and additive risk dose-response models implemented with both Poisson and Cox regression. Potential confounding by birth cohort and smoking prevalence were also assessed. Lifetime cumulative exposure and highest monthly exposure were the dose metrics evaluated. The estimated lifetime additional risk of lung cancer mortality associated with 45 years of occupational exposure to 1 microg/m3 Cr(VI) (occupational exposure unit risk) was 0.00205 (90%CI: 0.00134, 0.00291) for the relative risk model and 0.00216 (90%CI: 0.00143, 0.00302) for the additive risk model assuming a linear dose response for cumulative exposure with a five-year lag. Extrapolating these findings to a continuous (e.g., environmental) exposure scenario yielded an environmental unit risk of 0.00978 (90%CI: 0.00640, 0.0138) for the relative risk model [e.g., a cancer slope factor of 34 (mg/kg-day)-1] and 0.0125 (90%CI: 0.00833, 0.0175) for the additive risk model. The relative risk model is preferred because it is more consistent with the expected trend for lung cancer risk with age. Based on statistical tests for exposure-related trend, there was no statistically significant increased lung cancer risk below lifetime cumulative occupational exposures of 1.0 mg-yr/m3, and no excess risk for workers whose highest average monthly exposure did not exceed the current Permissible Exposure Limit (52 microg/m3). It is acknowledged that this study had limited power to detect increases at these low exposure levels. These cancer potency estimates are comparable to those developed by U.S. regulatory agencies and should be useful for assessing the potential cancer hazard associated with inhaled Cr(VI). 相似文献
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Igor Yakovenko David C. Hodgins Nady el-Guebaly David M. Casey Shawn R. Currie Garry J. Smith 《International Gambling Studies》2016,16(2):175-192
Disordered gambling is best conceptualized as a continuum of severity. Previous research has demonstrated the utility of studying individuals at all points of this spectrum. The sequence of the development of gambling problems and change in gambling involvement along this continuum of severity is not well understood. The present study examined the interplay between cognitive distortions and gambling involvement in a population sample recruited in Alberta, Canada. Data from 1372 participants over 4 assessment waves (5 years) were used to generate a 2-factor latent structure using gambling fallacies and gambling involvement measurements. Structural equation modelling showed that cognitive distortions more strongly predicted future gambling involvement than the reverse relationship, using the comparative fit index (CFI) and the root mean square error of approximation (RMSEA) to assess the models. In addition, cognitive distortions declined over time, whereas gambling involvement remained stable. The results of the study suggest that focusing primarily on cognitive mechanisms in public health initiatives for gambling disorders may be a more effective strategy than focusing on behavioural solutions. 相似文献
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Marie‐Claude Salvas Frank Vitaro Mara Brendgen Éric Lacourse Michel Boivin Richard E. Tremblay 《Social Development》2011,20(4):645-663
The aim of this study was to investigate the unique and combined role of friendship quality and friends' aggression in regard to the persistence of young children's physical aggression from kindergarten to grade 2. The sample included 1555 children (808 girls) assessed annually using teacher ratings. Two theoretical perspectives (i.e., the social learning and the social bonding perspectives) served as frameworks to guide the analyses and interpret the results. In line with the social learning perspective, friends' aggression was related to a significant increase in children's physical aggression. However, in line with the social bonding perspective, good friendship quality played both a compensatory and a protective role, by, respectively, reducing children's initial level of physical aggression and by mitigating, albeit marginally, the associations between friends' and children's physical aggression. These results suggest that fostering a positive relationship between friends in the early school years may decrease physical aggression even if the friends are aggressive. 相似文献
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This study examined several potential correlates of engagement and disengagement coping, including abuse-related factors, socioeconomic and social coping resources, and childhood trauma variables among a sample of battered women (N = 388). Relationship abuse frequency, particularly psychological aggression, and peritraumatic dissociation were the strongest positive predictors of the use of disengagement coping. Social coping resources, including tangible support and appraisals of social support and belonging, were associated with higher engagement coping and lower disengagement coping. A positive association was also found between interparental domestic violence and disengagement coping, and negative associations were found between both childhood physical and sexual abuse and engagement coping. Results suggest that coping strategies used by battered women are multidetermined and deserve further exploration. 相似文献
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Male and female participants were surveyed on abortion attitudes, commitment, and abortion experience. Results revealed a normal distribution of abortion attitudes rejecting the notion that the vast majority of the sample would have significantly pro-choice views. No significant difference was found in overall abortion attitudes of males vs. females, however, individuals with direct abortion experience were found to have significantly stronger pro-choice attitudes than individuals without direct abortion experience. Overall, college students reported a moderate degree of commitment to the issue of abortion. Females were significantly more committed than males, individuals with direct abortion experience were significantly more committed than individuals without direct abortion experience, and individuals with more extreme abortion attitudes were significantly more committed than those with weaker, more ambivalent, attitudes. No significant difference was found in level of commitment between pro-choice and pro-life individuals. 相似文献
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Patterns of Intimate Partner Violence and Sexual Risk Behavior among Young Heterosexually Active Men
Erin A. Casey Katherine Querna N. Tatiana Masters Blair Beadnell Elizabeth A. Wells Diane M. Morrison 《Journal of sex research》2016,53(2):239-250
Intimate partner violence (IPV) victimization is linked to sexual risk exposure among women. However, less is known about the intersection of IPV perpetration and sexual risk behavior among men. This study used data from a diverse, community sample of 334 heterosexually active young men, aged 18 to 25, across the United States to examine whether and how men with distinct IPV-related behavior patterns differed in sexual risk–related behavior and attitudes. Participants were recruited and surveyed online, and grouped conceptually based on the types of IPV perpetration behavior(s) used in a current or recent romantic relationship. Groups were then compared on relevant sexual risk variables. Men reporting both physical abuse and sexual coercion against intimate partners reported significantly higher numbers of lifetime partners, higher rates of nonmonogamy, greater endorsement of nonmonogamy, and less frequent condom use relative to nonabusive men or those reporting controlling behavior only. This group also had higher sexually transmitted infection (STI) exposure compared to men who used controlling behavior only and men who used sexual coercion only. Findings suggest that interventions with men who use physical and sexual violence need to account for not only the physical and psychological harm of this behavior but also the sexual risk to which men may expose their partners. 相似文献
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Frédéric Dussault Mara Brendgen Frank Vitaro René Carbonneau Michel Boivin Richard E. Tremblay 《Journal of gambling studies / co-sponsored by the National Council on Problem Gambling and Institute for the Study of Gambling and Commercial Gaming》2016,32(2):547-565
In both adolescents and adults, gambling problems and depressive symptoms co-occur and share some common risk factors (e.g., impulsivity and socio-family risk). However, little is known about (1) the developmental course of the co-morbidity of these problems; (2) variables that may moderate the effect of these common risk factors on gambling problems and depressive symptoms. Of specific interest could be individuals’ social relationships with significant others such as parents and friends, because research shows that they moderate the effect of other risk factors on gambling problems and depressive symptoms. The goals of this study were to: (a) identify developmental pathways for gambling problems and depressive symptoms, with a focus on co-morbidity; (b) assess the moderating effect of relationship quality with parents and friends on the link between common risk factors and the trajectories of gambling problems and depressive symptoms. Study participants were 878 males. Predictors were assessed during childhood and adolescence and gambling problems and depressive symptoms were assessed in late adolescence and young adulthood. Latent class analysis revealed four distinct joint trajectories of gambling problems and depressive symptoms. Subsequent logistic regression revealed that impulsivity predicted membership in all pathogenic trajectories, and quality of the relationship with parents predicted membership in depressogenic trajectories. In addition, we found that the membership in the comorbid trajectory can be predicted by an interaction between friendship quality and socio-family risk. 相似文献