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1.
Point-light and full-view short video clips of female walkers were displayed on a CRT monitor and male students rated the likelihood of selecting a walker for various advances. Relationships between the ratings, the walkers’ self-reported frequencies of being approached, gait cues, and self-rated personality traits were examined. In the point-light condition, raters selected slow walkers with a short stride length and personality traits implying vulnerability as targets for inappropriate touching. In the full-view condition, the raters selected fashionably groomed or physically attractive walkers as sexual advance targets. These criteria corresponded partially with reported occurrences of advances. Awkward movement impression was suggested as a kinematic gait quality influencing sexual advance target choice.  相似文献   
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In recent years, immunological science has evolved, and cancer vaccines are now approved and available for treating existing cancers. Because cancer vaccines require time to elicit an immune response, a delayed treatment effect is expected and is actually observed in drug approval studies. Accordingly, we propose the evaluation of survival endpoints by weighted log‐rank tests with the Fleming–Harrington class of weights. We consider group sequential monitoring, which allows early efficacy stopping, and determine a semiparametric information fraction for the Fleming–Harrington family of weights, which is necessary for the error spending function. Moreover, we give a flexible survival model in cancer vaccine studies that considers not only the delayed treatment effect but also the long‐term survivors. In a Monte Carlo simulation study, we illustrate that when the primary analysis is a weighted log‐rank test emphasizing the late differences, the proposed information fraction can be a useful alternative to the surrogate information fraction, which is proportional to the number of events. Copyright © 2016 John Wiley & Sons, Ltd.  相似文献   
3.
Many clinical research studies evaluate a time‐to‐event outcome, illustrate survival functions, and conventionally report estimated hazard ratios to express the magnitude of the treatment effect when comparing between groups. However, it may not be straightforward to interpret the hazard ratio clinically and statistically when the proportional hazards assumption is invalid. In some recent papers published in clinical journals, the use of restricted mean survival time (RMST) or τ ‐year mean survival time is discussed as one of the alternative summary measures for the time‐to‐event outcome. The RMST is defined as the expected value of time to event limited to a specific time point corresponding to the area under the survival curve up to the specific time point. This article summarizes the necessary information to conduct statistical analysis using the RMST, including the definition and statistical properties of the RMST, adjusted analysis methods, sample size calculation, information fraction for the RMST difference, and clinical and statistical meaning and interpretation. Additionally, we discuss how to set the specific time point to define the RMST from two main points of view. We also provide developed SAS codes to determine the sample size required to detect an expected RMST difference with appropriate power and reconstruct individual survival data to estimate an RMST reference value from a reported survival curve.  相似文献   
4.
There exist many studies which treat the inequality and/or interval constraints on coefficients in the homoscedastic linear regression model. However, the sampling performance of the inequality constrained estimators in the heteroscedastic linear model has not been examined. This paper considers the inequality constrained estimators in the heteroscedastic linear regression model and derives their risks under a quadratic loss function. Furthermore, using the inequality constrained estimators, we introduce a pre-test estimator which might be employed after the test for homoscedasticity and derive its risk. In addition, the risk performance of these estimators is evaluated numerically.  相似文献   
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The purpose of the present investigation 1s to observe the effect of departure from normahty of the prior distribution of regresslon parameters on the Bayman analysis of a h e a r regresslon model Assuming an Edgeworth serles prior distribution for the regresslon coefficients and gamma prior for the disturbances precision, the expressions for the posterlor distribution, posterlor mean and Bayes risk under a quadratic loss function are obtalned The results of a numerical evaluation are also analyzed  相似文献   
7.
In this paper we obtain the Bayes forecasts for the future observations on the dependent variable in the linear regression model when the regression coefficients have an Edgeworth series prior distribution. Furthermore, we consider the effect of departure from normality of the prior distribution of regression coefficients on the Bayes forecasts.  相似文献   
8.
The scope of economic theory expands if we consider that working provides people with both pecuniary compensation for its disutility and job satisfaction. This study empirically analyzes the job satisfaction of employees in Japanese private companies using a multivariate ordered probit model. In particular, we examine the effects of a big economic shock, such as the Lehman shock, on job satisfaction, as well as the effects of differences in gender and employment status. We estimate the model using a Bayesian analysis and a multivariate ordered probit model using the Markov chain Monte Carlo method. We show that non‐pecuniary aspects of jobs play an important role in job satisfaction.  相似文献   
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This paper considers the Bayesian analysis of a linear regression model with identically independently distributed non-normal disturbances. The distribution of disturbances is approximated by an Edgeworth series distribution with cumulants, of order higher than fourth, negligible. The posterior distribution of the regression coefficients vector is obtained under the assumption of a g-prior distribution for the parameters of the model. The Bayes estimator and its Bayes risk of the estimator are derived under a quadratic loss structure.  相似文献   
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