以读者为本，提升图书馆服务水平

以读者为本是图书馆落实科学发展观的客观要求，也是图书馆生存和发展的必然选择。图书馆应从服务理念的更新、服务环境的营造、服务工作的深化、读者权益的保护等方面来具体落实以读者为本的办馆理念，提升图书馆服务水平。     

金陵来取贤良士,岭表诸贤尽选抡--洪武荐举制度与诗文研究(上)

朱元璋统治期间 ,多次实施荐举制度。荐举制度的实行为文人聚会京师提供了契机 ,在一定程度上促进了文人诗文创作的提高 ,并且造成文人群中“组诗”的大量出现。同时荐举制度在诗文理论方面也产生了一定的效应     

基于Web日志和商品分类的协同过滤推荐系统

传统的协同过滤算法一般以用户对商品的评分作为研究,考虑到显式的评分数据一般很少能够取到,本文从记录用户浏览历史的服务器端日志文件以及客户购买历史数据作为数据源,根据商品分类进行评分矩阵设计,最后由此得到最近邻居从而给予个性化推荐,试验证明推荐效果比较显著。     

面向储能的光伏微网成本评价与对策研究

微电网是智能电网的重要组成部分,可以有效协调区域内的电力资源。为研究面向储能的光伏微网电力成本变化情况和优化对策,基于微网多主体结构构建微网电力成本均衡模型,以微网内分布式光伏供应及用户电力需求的统计数据为主要输入对象,并设置变量来区分不同情景下的分布式可再生能源发电量,建立以时间为自变量的微网分布式电力收益函数和用户购电成本函数,刻画微网电力资源调度的动态均衡变化。基于微网电力资源调度实例,发现微网在并网情景下的购电成本小于储能情景下的购电成本（C并=2 033.6元C储=2 633.6元）,且储能情景下购电成本的22.8%都来自储能设施的日折旧费,因此,加大科技研发和增强微网协同管理可以降低微网成本。     

平等服务和个性化信息服务——高校创建新型图书馆的两个核心理念

给读者提供平等的信息服务是现代图书馆首要的核心理念。现代网络信息技术恰好为个性化服务提供了方便。个性化服务需要图书馆员付出许多特殊的劳动,为保持服务平等性的纯洁,可采取适当对其提供了特殊服务的读者用服务收费的办法来实现平等服务的宗旨,以取得与普通读者平等的待遇,从而实现平等服务和个性化服务的两全其美。     

On evaluating how well a biomarker can predict treatment response with survival data

One of the objectives of personalized medicine is to take treatment decisions based on a biomarker measurement. Therefore, it is often interesting to evaluate how well a biomarker can predict the response to a treatment. To do so, a popular methodology consists of using a regression model and testing for an interaction between treatment assignment and biomarker. However, the existence of an interaction is not sufficient for a biomarker to be predictive. It is only necessary. Hence, the use of the marker‐by‐treatment predictiveness curve has been recommended. In addition to evaluate how well a single continuous biomarker predicts treatment response, it can further help to define an optimal threshold. This curve displays the risk of a binary outcome as a function of the quantiles of the biomarker, for each treatment group. Methods that assume a binary outcome or rely on a proportional hazard model for a time‐to‐event outcome have been proposed to estimate this curve. In this work, we propose some extensions for censored data. They rely on a time‐dependent logistic model, and we propose to estimate this model via inverse probability of censoring weighting. We present simulations results and three applications to prostate cancer, liver cirrhosis, and lung cancer data. They suggest that a large number of events need to be observed to define a threshold with sufficient accuracy for clinical usefulness. They also illustrate that when the treatment effect varies with the time horizon which defines the outcome, then the optimal threshold also depends on this time horizon.     

A visualization method measuring the performance of biomarkers for guiding treatment decisions

Biomarkers that predict efficacy and safety for a given drug therapy become increasingly important for treatment strategy and drug evaluation in personalized medicine. Methodology for appropriately identifying and validating such biomarkers is critically needed, although it is very challenging to develop, especially in trials of terminal diseases with survival endpoints. The marker‐by‐treatment predictiveness curve serves this need by visualizing the treatment effect on survival as a function of biomarker for each treatment. In this article, we propose the weighted predictiveness curve (WPC). Based on the nature of the data, it generates predictiveness curves by utilizing either parametric or nonparametric approaches. Especially for nonparametric predictiveness curves, by incorporating local assessment techniques, it requires minimum model assumptions and provides great flexibility to visualize the marker‐by‐treatment relationship. WPC can be used to compare biomarkers and identify the one with the highest potential impact. Equally important, by simultaneously viewing several treatment‐specific predictiveness curves across the biomarker range, WPC can also guide the biomarker‐based treatment regimens. Simulations representing various scenarios are employed to evaluate the performance of WPC. Application on a well‐known liver cirrhosis trial sheds new light on the data and leads to discovery of novel patterns of treatment biomarker interactions. Copyright © 2015 John Wiley & Sons, Ltd.     

关于做好电视成就报道的思考

文章着重探讨了电视成就报道的创新方法,在理念上提出以个性化的受众为中心、结合电视传播特点、贴近工作实际;具体方法上则提出以四个方面为突破口,即:通过个人化的视角,贴近生活;用理性思维诠释热点;用情节化的叙述,加深人们的理解;调动多种电视表现手段,增强视觉冲击力.     

博客平台下的网评结构语言特点

相比BBS等传统网评的空间载体,博客作为一个私有性较强的平台,面向的是个人、朋友及具有共同目标的群组,在web2．0技术的支持下,它的网评结构语言出现了新特点。一方面,博客作者的原创评论日志更具理性、逻辑条理性,同时夹杂大量情感与生活经历背景,带有个人化论述的印记;另一方面,博客读者对日志的评论围绕日志文本一个中心展开,在群组性社会关系网络的支撑下,主要以友善、鼓励性话语为主,形成网络“熟人社会”交流的新形式。     

高校图书馆数字参考咨询现状分析及研究

介绍数字参考咨询服务的概念、特征、内容及其与传统咨询服务的异同,指出高校数字参考咨询服务存在技术、数据库建设、人才、服务质量、知识产权保护等方面的问题,并提出解决这些问题的相应对策和建议。