Determination of oxidative stress levels and some antioxidant enzyme activities in prostate cancer

In this study, the antioxidant enzyme activities such as (SOD, GSH, and CAT) and malondialdehyde (MDA) level which is the end product of lipid peroxidation, were determined from the serum samples taken from patients diagnosed with prostate cancer Van Yuzuncu Y?l University Medical Faculty of Educational Research and Training Hospital and ?stanbul Bagcilar Education Research Hospital. The SOD, GSH, and CAT activity of patient groups was found significantly lower than the healthy control group in patients with prostate cancer (p?相似文献   

Maternal and paternal reactions to child sadness predict children's psychosocial outcomes: A family‐centered approach

Parents' reactions to children's emotions shape their psychosocial outcomes. Extant research on emotion socialization primarily uses variable‐centered approaches. This study explores family patterns of maternal and paternal responses to children's sadness in relation to psychosocial outcomes in middle childhood. Fifty‐one families with 8‐ to 12‐year‐old children participated. Mothers and fathers reported their reactions to children's sadness and children's social competence and psychological adjustment. Cluster analyses revealed three family patterns: Supportive (high supportive and low non‐supportive reactions from both parents), Not Supportive (low supportive reactions from both parents), and Father Dominant (high paternal supportive and non‐supportive reactions, low maternal supportive and non‐supportive reactions). Supportive families had children with higher social competence and more internalizing symptoms whereas Father Dominant families had children with lower social competence and fewer internalizing symptoms. Not Supportive families had children with average social competence and fewer internalizing symptoms. Findings are discussed in relation to the “divergence model” which proposes that a diverse range of parental responses to children's sadness, rather than a uniformly supportive approach, may facilitate children's psychosocial adjustment.     

蛋白组学方法应用于人肺癌组织蛋白表达的研究

采用蛋白组学方法,利用4例中国肺癌患者的切除肺癌组织测定了磷癌(SQCLC)的蛋白表达 从双向电泳(2-DEgel)切下53个点,49个蛋白与数据库搜索结果吻合。在鉴定的24个蛋白中,17个蛋白有报道是与肺癌相关的蛋白其7个蛋白与人类其它癌症相关。所建立的蛋白组学方法能够用于建立一种基于组织的化验方法,发现肺癌患者组织中表达的蛋白标记物以用于癌症的分子学诊断。     

王安忆小说中的童年意象

童年意象的运用是王安忆小说独树一帜的重要原因."成长中的儿童"是王安忆小说中特有的形象.以儿童形象为象征载体进行文化批判是对童年意象的出色运用.儿童视角的发掘使王安忆的小说取得了"陌生化"的审美效果,也使细节化呈现文本的艺术表达方式与文本的精神内涵完美地结合起来.儿童视角的运用还让作家能以旁观者的眼光看世界,保持了独立、警醒的创作立场.     

乡村振兴视域下陶行知乡村幼儿教育思想的当代启示

乡村振兴是一项长期持久的复杂系统工程,全面助力乡村振兴,农村幼儿教育先行。近年来,我国高度重视农村幼儿教育发展,但因多种因素制约,当前我国农村幼儿教育发展急需解决关键问题,突破诸多困境。早在20世纪二三十年代,我国人民教育家陶行知先生就已独到地认识到我国乡村幼儿教育的重要性及其存在的问题,并在实验和探索中形成了著名的乡村幼儿教育思想,这一思想与乡村振兴战略中优先发展农村教育的思想高度契合。乡村振兴视域下回顾陶行知的乡村幼儿教育思想,对于当前我国农村幼儿教育发展及全面实施乡村振兴战略具有极强的现实启示。     

个体身份与生命意义：肺癌网络社区的疾病叙事

文章通过对国内"医享网"癌症社区"肺癌圈"中33篇精华帖的叙事分析,探究其中生命故事的主体对自我身份的建构路径及其对生命价值的意义探寻,并尝试性地提出一些反思。研究发现,在自述和他述生命故事中,叙事者在信息寻求过程中改善自我印象,并运用"写作疗法""阅读疗法"和叙事隐喻理解疾病,帮助患者重塑自身角色。通过社群互动,患者形塑了对自身的身份认同,并形成了集体层面的生命价值观。从本研究的结论看,疾病叙事是癌症网络社区患者建构个体身份、形成身份认同的重要途径,叙事或可成为未来增进社会对癌症乃至其他疾病的理解、推进治疗与康复的可行之路。     

Goffman,Growing Up,and Experienced Relationality

This article adopts a Goffmanian framework to grapple with the emotional‐relational experiences associated with teenagers growing up. Drawing upon focus group interviews with 14–15 year olds in East and West Belfast, the lack of full personhood attributed to nonadults is discussed in relation to spatial exclusion and stigmatizing service transactions, along with some emotional consequences. However, instances where teenagers embrace as well as reject this ostensibly negative social positioning are also elaborated. The overall thrust of the article seeks to demonstrate how the hierarchical adult‐child complex is built and maintained through everyday face‐to‐face interaction and the ritualistic expression of standards of worth assigned to participants.     

Costs of promoting cancer screening: Evidence from CDC’s Colorectal Cancer Control Program (CRCCP)

The Colorectal Cancer Control Program (CRCCP) provided funding to 29 grantees to increase colorectal cancer screening. We describe the screening promotion costs of CRCCP grantees to evaluate the extent to which the program model resulted in the use of funding to support interventions recommended by the Guide to Community Preventive Services (Community Guide). We analyzed expenditures for screening promotion for the first three years of the CRCCP to assess cost per promotion strategy, and estimated the cost per person screened at the state level based on various projected increases in screening rates. All grantees engaged in small media activities and more than 90% used either client reminders, provider assessment and feedback, or patient navigation. Based on all expenditures, projected cost per eligible person screened for a 1%, 5%, and 10% increase in state-level screening proportions are $172, $34, and $17, respectively. CRCCP grantees expended the majority of their funding on Community Guide recommended screening promotion strategies but about a third was spent on other interventions. Based on this finding, future CRC programs should be provided with targeted education and information on evidence-based strategies, rather than broad based recommendations, to ensure that program funds are expended mainly on evidence-based interventions.     

肺癌患者血清同型半胱氨酸变化的临床意义

目的：探讨血清同型半胱氨酸在肺癌患者中的变化及临床意义。方法检测82例住院治疗肺癌患者和79例健康体检者空腹血清同型半胱氨酸水平。结果分析得出肺癌组的血清Hcy含量显著高于健康对照组，差异有统计学意义（P＜0.01）。Ⅰ～Ⅳ期肺癌的患者血清Hcy含量均显著高于健康组（P＜0.01）。结论血清Hcy可做为肺癌的病情诊断、疗效预后的辅助指标。