泰乐松注射液的毒理学试验研究

为提供泰乐松注射液的安全性毒理学评价资料,本试验采用改进Karber法测定小鼠LD_(50);以剂量递增法测定小鼠蓄积性和耐受性;分别以剂量340、130、30mg／kg为3个试验组．设阴性和阳性对照组进行小鼠骨髓微核试验;分别以剂量500、250、120mg／kg为3个剂量组．设阴性和阳性对照组进行小鼠精于畸形试验。结果表明：其LD_(50)为669．80mg／kg,蓄积系数大于5．3,无明显蓄积毒性和耐受性（P＞0．05）,小鼠骨髓微核试验和精子畸形试验结果均为阴性。     

Economic Viability Among Post-Retirement Aged Women

Longer life expectancy has increased concern about living standards among elder women. This paper examines the relation between labor market status and living standard post-retirement. We use data from two national surveys to contrast economic circumstances of post-retirement aged and currently employed women. Financial resources of aged women and factors associated with their magnitude are identified. We examine current economic resources and employee benefits of women who will retire after the year 2000. The paper concludes with a discussion of proactive mid-life strategies for long-term economic stability among women, with emphasis on unique concerns, of black women.     

The Protective Impact of a Covariate on Competing Failures with an Example from a Bone Marrow Transplantation Study

Starting from an applied Bone Marrow Transplantation(BMT) study, the problem of “unexpected protectivity” in competing risks models is introduced, which occurs when one covariate shows a protective impact not expected from a medical perspective. Current explanations found in the statistical literature suggest that unexpected protectivity might be due to the lack of independence between the competing failures. Actually, in the presence of dependence, the Kaplan-Meier curves are not interpretable. Conversely, the cumulative incidence curves remain interpretable, and therefore seem to be a candidate for solving the problem. We discuss the particular nature of dependence in a competing risks framework and illustrate how this dependence may be created via a common frailty factor. A Monte Carlo experiment is set up which accounts also for the association between the observable covariates and the frailty factor. The aim of the experiment is to understand whether and how the bias showed by the estimates could be related to the omitted frailty variable. The results show that dependence alone does not cause false protectivity, and that the cumulative incidence curves suffer the same bias as the survival curves and therefore do not seem to be a solution to false protectivity. Conversely, false protectivity may occur according to the magnitude and the sign of the dependence between the frailty factor and the covariate. The paper ends with some suggestions for empirical research. This revised version was published online in July 2006 with corrections to the Cover Date.     

“骨”之意象解读——对伍慧明小说《骨》的主题研究

美国华裔女性作家伍慧明是美国文坛上近几年出现的后起之秀,她的处女作《骨》深刻描述了美国华裔生活的新经历,受到广泛关注和好评。在小说中她将“骨”这一简单意象作为贯穿全文的一条主线,以简洁的文字深入探讨了华裔美国人的多元文化属性问题,以多重对话的方式使个人、家庭历史得以再现,向以白人为主导的强势文化及父权中心发起挑战,同时对中西方文化的融合与冲撞予以反思,从而表现出美国华裔移民在双重文化环境中寻找文化认同、确定文化属性的艰辛及不懈努力。     

骨笛神韵--8000年前骨笛研究

1986年，兴隆洼文化遗址出土一支骨笛，经专家研究鉴定、修复、测音、演奏，证明了它是中国远古时期最早的乐器之一。证明中国音乐的历史和乐器制作史，距今已有8000多年，同时还证明了8000年前中国音乐的构成，不仅有5声音阶、6声音阶，还有7声音阶，把中国7声音阶的历史提前到了8000年前。对推动中华文明的探源工程有着极为深远的意义，对进一步研究中国乃至世界音乐史意义重大。     

Clinical effects of growth hormone on bone: a review

Growth hormone (GH) stimulates bone turnover. Deficiency of GH due to hypopituitarism is related to low bone mineral density and increased fracture risk. GH substitution increases and thus normalizes bone mineral density in these patients, which is one of a number of arguments for GH substitution in hypopituitarism. In contrast, a possible therapeutic use of GH in idiopathic osteoporosis and glucocorticoid-induced osteoporosis is speculative and not established. Reduction of osteoporosis risk is an argument brought up for a use of GH in healthy elderly persons (anti-aging medicine). However, since only very limited data are available yet, this cannot be based on scientific evidence, and there are important concerns about the safety of use of GH in healthy elderly persons.     

《尧典》与甲骨卜辞的叹词"俞"

考察了甲骨文中的叹词"俞"和先秦《尚书》中的叹词"俞"的情况,先秦其它古籍少有"俞"这个叹词,由此可证《尚书》之《尧典》来源很古。     

老年妇女骨质疏松性髋部骨折的危险性预测

目的探讨老年妇女骨质疏松性髋部骨折的危险性因素,建立判别方程,为预测老年妇女骨质疏松性髋部骨折提供依据.方法以髋部骨折老年女性患者及保健体检的老年妇女各30例为研究对象,分为观察组和对照组.测量所有样本髋部BMD(病例组为健侧,对照组为左侧)、颈干角(NSA)、左手握拳力;根据身高体重算出BMI;确定个人及家族女性骨折史.通过logistic回归分析及判别分析,进行统计学处理.结果老年妇女骨质疏松性髋部骨折的危险因素为:ward区BMD、NSA、BMI、左手握拳力;老年妇女骨质疏松性髋部骨折的危险性判别方程:Y1=-8.802×X1 88.803×X2 9.936×X3 8.119×X4 2.634×X5 22.439×X6-691.647,Y0=-9.901×X1 93.959×X2 15.872×X3 8.045×X4 3.037×X5 23.533×X6-696.284;将判别方程进行组内回代检验,特异度为76.7%,灵敏度为86.7%,预测正确率为81.7%.结论通过判别方程能够预测老年妇女骨质疏松性髋部骨折的危险性.     

甲骨文工具书综论

甲骨文工具书产生于考释书的基础上,但不同于甲骨文考释书,也不同于甲骨文著录书和甲骨学工具书。根据内容、体例的不同,甲骨文工具书可以区分为汇集字形为主的字汇类、综合考释意见的会要类、罗列卜辞的索引类、解释字形字义词义的字典类等四种类型。甲骨文工具书应体现“完备、赅实、准确、方便”的特点。     

论中国龙源于恐龙

早期龙与恐龙形体的相似以及龙文化与恐龙化石产地的一致,说明中国龙的原型是恐龙石。文字史料更证实古代开垦者曾多次发现过恐龙化石,正是这些巨大的骨骼化石的发现,使古人确信了这种动物的真实存在,并依据恐龙化石创造了龙的形象,中国龙实际上是古代中国人对恐龙的复原。