A-H键振动频率与原子价层轨道能

本文研究了原子价层轨道能与共价型分子氢化物中A-H键的振动频率v_(A-H)的关系,结果表明二者间有良好的线性关系,其计算式为: v_(A-H)=-a∑n_1E_1/∑n_1(A)+b (1) V_(A-H)=-c∑n_1E_1/∑n~(B)+d (2)利用上式计算的振动频率V_(A-H)值接近于文献值。从而验证了用韩长日方法计算电负性的合理性。     

Residual analysis for spatial point processes (with discussion)

Summary.  We define residuals for point process models fitted to spatial point pattern data, and we propose diagnostic plots based on them. The residuals apply to any point process model that has a conditional intensity; the model may exhibit spatial heterogeneity, interpoint interaction and dependence on spatial covariates. Some existing ad hoc methods for model checking (quadrat counts, scan statistic, kernel smoothed intensity and Berman's diagnostic) are recovered as special cases. Diagnostic tools are developed systematically, by using an analogy between our spatial residuals and the usual residuals for (non-spatial) generalized linear models. The conditional intensity λ plays the role of the mean response. This makes it possible to adapt existing knowledge about model validation for generalized linear models to the spatial point process context, giving recommendations for diagnostic plots. A plot of smoothed residuals against spatial location, or against a spatial covariate, is effective in diagnosing spatial trend or co-variate effects. Q – Q -plots of the residuals are effective in diagnosing interpoint interaction.     

DNA分子近邻互补链碱基的非线性效应

DNA分子近邻互补链碱基的非线性动力学效应研究，综述了Yomosa及Zhang模型，并在改进后的平面转子模型基础上，利用阶乘矩分析方法分析了平面转子模型的非线性效应，结果说明该模型更好的近似性．     

测定二氧化碳分子量的微型实验

利用自制的简易气体发生器和洗气装置对二氧化碳分子量测定微型实验作了进一步的探索和实践、测定结果不仅达到无机化学实验对测定精度的要求。而且更便于推广和普及．     

Improved Monte Carlo inference for models with additive error

Some statistical models defined in terms of a generating stochastic mechanism have intractable distribution theory, which renders parameter estimation difficult. However, a Monte Carlo estimate of the log-likelihood surface for such a model can be obtained via computation of nonparametric density estimates from simulated realizations of the model. Unfortunately, the bias inherent in density estimation can cause bias in the resulting log-likelihood estimate that alters the location of its maximizer. In this paper a methodology for radically reducing this bias is developed for models with an additive error component. An illustrative example involving a stochastic model of molecular fragmentation and measurement is given.     

DNA芯片技术

DNA芯片可用于核酸序列的测定及基因突变检测等,这里对DNA芯片的制作、作用原理、性能及用途等进行了综述。     

从群体遗传的DNA线索看东乡族族源问题

DNA分析技术的发展为进行民族识别和分析民族起源、迁徙、流动、融合提供了新手段。本文在国内外首次应用D13S317基因座第 11号等位基因频率指标 ,计算了东乡族群体遗传动态数据。结果发现 ,东乡族和回族遗传距离很近 ,且东乡族中具有白种人血缘混杂。结合其他有关资料 ,我们认为东乡族的起源与元代蒙古军带来的中亚工匠、签军有关 ,亦与当地蒙古族、回族、藏族人群的融合有关。本文的研究结果可以为民族研究提供群体遗传方面的线索     

农科博士生《植物分子生物学进展》课程教学方法的探讨

农科博士生《植物分子生物学进展》是一门旨在植物分子生物学领域提高博士生独立科研能力和开阔博士生科研视野的一门课程,本文从教学内容、考核方法、教学形式等三方面内容对该课程的教学方法进行了阐述和探讨。     

Generalized Augmentation to Control the False Discovery Exceedance in Multiple Testing

Abstract.  A new multiple testing procedure, the generalized augmentation procedure (GAUGE), is introduced. The procedure is shown to control the false discovery exceedance and to be competitive in terms of power. It is also shown how to apply the idea of GAUGE to achieve control of other error measures. Extensions to dependence are discussed, together with a modification valid under arbitrary dependence. We present an application to an original study on prostate cancer and on a benchmark data set on colon cancer.