基于互信息的功能磁共振图像配准

互信息作为衡量两幅图像配准的相似性测度函数,当两幅图像配准时,互信息达到最大值。该文提出了基于互信息脑功能磁共振图像配准新方法,采用了无需计算梯度的Powell直接搜索算法,并通过多分辨的方式加快了图像配准速度。磁共振的配准实验证明,互信息法能准确地实现多模态医学图像的配准,并且能达到亚像素的精度。     

Identifying Skeleton Curves in Noisy Data

This article presents a Bayesian method to reconstruct the centerline in noisy data using B-spline curves. The method is illustrated on simulated two- and three-dimensional data and is applied to recover the centerline of the colon in single photon emission computed tomography images.     

对马克思主义理论整体性问题研究的反思及其现实意义

整体性是马克思主义理论的重要特性,整体性问题是研究马克思主义的一个基本问题,也是当前我国学者研究马克思主义的一个热点问题。我国理论界围绕此问题进行了深入而系统的研究,取得了丰硕成果,但也存在一些问题,对这些问题的反思,有益于进一步实现马克思主义整体发展和创新的前瞻性使命。     

基于灰色系统的小型精密机床热误差模型

为减少热误差对数控机床加工精度的影响,文章利用灰色系统研究热误差建模。初步分析机床热源后,应用灰 色关联度分析结合模糊分类方法优化得到13组关键温度测点,结合小型精密五轴机床处于实际加工状态时的实验数 据,应用GM(I,N)灰色结构进行建模。将实际数据与拟合数据进行对比分析,结果表明此灰色系统模型具有计算方法 成熟、鲁棒性强的特点,适用于机床热误差研究。     

Sex differences in the development of mild cognitive impairment and probable Alzheimer’s disease as predicted by hippocampal volume or white matter hyperintensities

This study examined biological sex differences in the development of mild cognitive impairment (MCI) and probable Alzheimer’s disease (AD) development as predicted by changes in the hippocampus or white matter hyperintensities. A secondary data analysis of the National Alzheimer’s Coordinating Center Uniform Data Set was conducted. We selected samples of participants with normal cognition at baseline who progressed to MCI (n = 483) and those who progressed to probable AD (n = 211) to determine if hippocampal volume or white matter hyperintensities (WMH) at baseline predicted progression to probable AD or MCI and whether the rate of progression differed between men and women. The survival analyses indicated that changes in hippocampal volumes affected the progression to probable AD (HR = 0.535, 95% CI [0.300–0.953]) only among women. White men had an increased rate of progression to AD (HR = 4.396, CI [1.012–19.08]; HR = 4.665, 95% CI [1.072–20.29]) compared to men in other race and ethnic groups. Among women, increases in hippocampal volume ratio led to decreased rates of progressing to MCI (HR = 0.386, 95% CI [0.166–0.901]). Increased WMH among men led to faster progression to MCI (HR = 1.048. 95% CI [1.011–1.086]). Women and men who were older at baseline were more likely to progress to MCI. In addition, results from longitudinal analyses showed that women with a higher CDR global score, older age at baseline, or more disinhibition symptoms experienced higher odds of MCI development. Changes in hippocampal volumes affect the progression to or odds of probable AD (and MCI) more so among women than men, while changes in WMH affected the progression to MCI only among men.     

数字多声束形成技术

医用超声诊断设备中存在两种声束形成技术。近年来在少数几个高档设备中使用了数字声束形成技术。正交分解是获得复包络信号的幅度和相位的关键，而数字延迟是数字电子聚焦所必须的。文中介绍了数字多声束形成的原理及应用。     

虚拟成像技术在林业科普中的应用研究——以“绿色微型生态”科普展示系统为例

数字科普是未来林业科普发展的主要方向。数字科普具有内容生动、形式多样、互动灵活等特点,相对于传统科普形式而言更有吸引力,能达到更好的科普效果。虚拟成像技术作为目前最有影响力的数字技术之一,将在林业科普的数字化进程中起到不可估量的作用。以"绿色微型生态"科普展示系统为例,通过分析该系统的设计思路、制作过程、实现功能和虚拟成像技术在该系统中的具体应用,探讨虚拟成像技术在林业科普领域的应用情况,研究林业科普产品的数字化创新方向,以及虚拟成像技术在林业科普数字化进程中的重要作用。     

平面热源法瞬态测量材料热物性的研究

简述了平面热源法瞬态测量材料热物理性质的基本原理,分析了快速法、脉冲法测量存在的问题。在此基础上,研究了材料热物性瞬态自动测量技术。测量实践表明:瞬态自动测量仪测量准确可靠,与用防护热板法测量的结果也符合得很好。     

位移边界对2D-FGM板热应力影响研究

考虑不同的位移边界条件,建立了常物性2D-FGM板研究模型,并采用有限元法,得到其冷却瞬态热应力场分布图形。位移边界条件对常物性2D-FGM平面区域冷却瞬态热应力分布影响颇大,在简支和一端固定情况下,2D-FGM板自由边界上的热应力σ_x=0;两端固定情况下,其左右两边界均形成上中下三个应力聚集,应力分布形状和数值都发生了巨大的变化;将四周均设置呈固定约束后,热应力数值增长幅度较两端固定情况时更为明显。此结果为该材料的设计、制备提供了准确的理论计算依据。     

Medicare and Amyloid PET Imaging: The Battle Over Evidence

We examine a recent dispute regarding the Centers for Medicare and Medicaid Services’ (CMS) refusal to unconditionally pay for amyloid positron emission tomography (PET) imaging for Medicare beneficiaries being assessed for Alzheimer’s disease. CMS will only pay for amyloid PET imaging when patients are enrolled in clinical trials that meet certain criteria. The dispute reflects CMS’s willingness in certain circumstances to require effectiveness evidence that differs from the Food and Drug Administration’s standard for pre-market approval of a medical intervention and reveals how stakeholders with differing perspectives about evidentiary standards have played a role in attempting to shape the Medicare program’s coverage policies.