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In disease screening and diagnosis, often multiple markers are measured and combined to improve the accuracy of diagnosis. McIntosh and Pepe [Combining several screening tests: optimality of the risk score, Biometrics 58 (2002), pp. 657–664] showed that the risk score, defined as the probability of disease conditional on multiple markers, is the optimal function for classification based on the Neyman–Pearson lemma. They proposed a two-step procedure to approximate the risk score. However, the resulting receiver operating characteristic (ROC) curve is only defined in a subrange (L, h) of false-positive rates in (0,1) and the determination of the lower limit L needs extra prior information. In practice, most diagnostic tests are not perfect, and it is usually rare that a single marker is uniformly better than the other tests. Using simulation, I show that multivariate adaptive regression spline is a useful tool to approximate the risk score when combining multiple markers, especially when ROC curves from multiple tests cross. The resulting ROC is defined in the whole range of (0,1) and is easy to implement and has intuitive interpretation. The sample code of the application is shown in the appendix.  相似文献   
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In recent times, the problem of prediction of properties of a steel strip has attracted enormous attention from different communities such as statistics, data mining, soft computing, and engineering. This is due to the prospective benefits of reduction in testing and inventory cost, increase in yield, and improvement in delivery compliance. The complexity of the problem arises due to its dependency on the chemical composition of the steel, and a number of processing parameters. To predict the mechanical properties of the strip (yield strength, ultimate tensile strength, and Elongation), a model based on multivariate adaptive regression spline has been developed. It is found that the prediction agrees well with the actual measured data.  相似文献   
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Recent developments of multivariate smoothing methods provide a rich collection of feasible models for nonparametric multivariate data analysis. Among the most interpretable are those with smoothed additive terms. Construction of various methods and algorithms for computing the models have been the main concern in literature in this area. Less results are available on the validation of computed fit, instead, and many applications of nonparametric methods end up in computing and comparing the generalized validation error or related indexes. This article reviews the behaviour of some of the best known multivariate nonparametric methods, based on subset selection and on projection, when (exact) collinearity or multicollinearity (near collinearity) is present in the input matrix. It shows the possible aliasing effects in computed fits of some selection methods and explores the properties of the projection spaces reached by projection methods in order to help data analysts to select the best model in case of ill conditioned input matrices. Two simulation studies and a real data set application are presented to illustrate further the effects of collinearity or multicollinearity in the fit.  相似文献   
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针对电机安装机械传感器不便的问题提出了新的速度辨识方法.从自适应控制原理和扩展卡尔曼滤波算法原理入手,将这两种不同的观测器应用于异步电机直接转矩控制,并对其进行研究和比较,找出各自的优缺点,利用Matlab/Simulink构建了系统的模型并进行仿真研究.结果表明:在负载变化、噪声抑制等方面EKF优于MARS;在状态观测方面,采用MARS优于EKF.  相似文献   
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