高效液相色谱—核磁共振联用技术

本文简要地综述了高效液相色谱与核磁共振联用技术,并列举了该技术在药物、天然产物以及异构体研究中的应用。     

短波近红外光谱的盐酸环丙沙星粉末药品的定量分析

利用漫反射法获得环丙沙星短波近红外光谱(700-1100nm),采用化学计量学中的偏最小二乘法(PLS),选取不同的波长范围及不同的光谱预处理方法(一阶导数和和二阶导数)对光谱进行信息提取和分析,对盐酸环丙沙星粉末药品进行了无损非破坏定量分析,以样品中盐酸环丙沙星为活性成分建立了最佳的数学校正模型。讨论了主成分数对PLS模型定量预测能力的影响,并做了比较。     

有机同系物的一个同系线性规律

对有机同系物的同系线性规律进行了探讨,提出了有机同系物的一种同系线性规律,其表达式为,并用有机共轭体系和双向共轭同系物的光电子能谱数据对该线性规律进行了验证。     

Exact and approximate distributions for linear contrasts of means and variances

A Bayesian analysis is presented for the K-group Behrens-Fisher problem. Both exact posterior distributions and approximations were developed for both a general linear contrast of the K means and the K variances, given either proper diffuse or informative conjugate priors. The contrast of variances is a unique feature of the heterogeneous variance model that enables investigators to test specific effects of experimental manipulations on variance. Finally, important-differences were observed between the heterogeneous variance model and the homogeneous model.     

运用表面光电压技术对半导体表面光电特性的研究

对运用表面光电压技术(SPS)对半导体材料光电性质的研究进行了综述,系统阐述了表面光电压谱(SPS)和场诱导表面光电压谱(FISPS)在测定半导体类型、表面态及其能级位置、表面电荷分布、半导体的能带隙等方面所表现出的优越性质.研究了半导体能带隙所表现出的特有性质.     

无穷级数比值判别法的推广

给出了正项级数关于敛散性的一个新的判别法 ,这一方法推广了达朗贝尔比值判别法     

Integrated marked Poisson processes with application to image correlation spectroscopy

Image correlation spectroscopy (ICS) is an experimental technique used in the study of cell tissue, specifically to obtain information about protein aggregates. This paper discusses a filtered Poisson process model of ICS, and uses this to obtain the sampling distribution of an estimator of interest, using spectral methods. Integrals of third- and fourth-order spectra are involved, and methods proposed in the literature are studied numerically. They are found to be infeasible methods, requiring months of computing time. An alternative method is proposed and is illustrated on some actual ICS experiments. A novel feature in this study is the use of a SIMD-class parallel computer, a MasPar MP-2 machine, to obtain some statistical properties of the estimation method.     

发散性思维与公共管理

发散性思维是一种创新思维,它有三种表现形式:多向思维、反向思维和交叉思维,具有流畅性、变通性、独特性三个特点;发散性思维之于公共管理,就在于指导公共管理人员学会思维创新,明确客体发散思维和主体发散思维的特点,掌握正确的发散性思维的方法,从而以发散性思维作导向,在公共管理实践中求实求新,富有创意.     

Using unlabelled data to update classification rules with applications in food authenticity studies

Summary.  An authentic food is one that is what it purports to be. Food processors and consumers need to be assured that, when they pay for a specific product or ingredient, they are receiving exactly what they pay for. Classification methods are an important tool in food authenticity studies where they are used to assign food samples of unknown type to known types. A classification method is developed where the classification rule is estimated by using both the labelled and the unlabelled data, in contrast with many classical methods which use only the labelled data for estimation. This methodology models the data as arising from a Gaussian mixture model with parsimonious covariance structure, as is done in model-based clustering. A missing data formulation of the mixture model is used and the models are fitted by using the EM and classification EM algorithms. The methods are applied to the analysis of spectra of food-stuffs recorded over the visible and near infra-red wavelength range in food authenticity studies. A comparison of the performance of model-based discriminant analysis and the method of classification proposed is given. The classification method proposed is shown to yield very good misclassification rates. The correct classification rate was observed to be as much as 15% higher than the correct classification rate for model-based discriminant analysis.     

The portfolio choice problem: comparison of certainty equivalence and optimal Bayes portfolios

For the portfolio problem with unknown parameter values, we compare the conventional certainty equivalence portfolio choice with the optimal Bayes portfolio. In the important single risky asset case a diffuse Bayes rule leads to portfolios that differ significantly from those suggested by a certainty equivalence rule which we show are inadmissible relative to a quadratic utility function for the range of parameters we consider. These results are invariant to arbitrary changes in the utility function parameters. We illustrate the results using a simple mutual fund example.