一类带有分布参数系统的最佳控制

本文给出一类非均匀弦的横向振动的最佳控制，推广了P C Park的结果。这一结果同样适用于同类型振动问题。     

校园网与现代教育

探讨了校园网和现代教育的关系 ,校园网络可以成为现代教育的平台和核心 ,围绕着校园网建设面向未来的现代教育 ,着重阐述了校园网络建设应该注意的问题。     

实用电源变压器检测台

该电路设计简单、构思新颖 ,适合小批量测试小型电源变压器的空载电流、额定电流及次级空载电压、满载电压、负载电流等参数     

ASSESSING CONGRUENCEAMONG DISTANCE MATRICES: SINGLE-MALT SCOTCH WHISKIES REVISITED

A test of congruence among distance matrices is described. It tests the hypothesis that several matrices, containing different types of variables about the same objects, are congruent with one another, so they can be used jointly in statistical analysis. Raw data tables are turned into similarity or distance matrices prior to testing; they can then be compared to data that naturally come in the form of distance matrices. The proposed test can be seen as a generalization of the Mantel test of matrix correspondence to any number of distance matrices. This paper shows that the new test has the correct rate of Type I error and good power. Power increases as the number of objects and the number of congruent data matrices increase; power is higher when the total number of matrices in the study is smaller. To illustrate the method, the proposed test is used to test the hypothesis that matrices representing different types of organoleptic variables (colour, nose, body, palate and finish) in single‐malt Scotch whiskies are congruent.     

Estimation of noncentrality parameters

We propose some estimators of noncentrality parameters which improve upon usual unbiased estimators under quadratic loss. The distributions we consider are the noncentral chi-square and the noncentral F. However, we give more general results for the family of elliptically contoured distributions and propose a robust dominating estimator.     

Estimation of Metabolic Rate Constants in PBPK‐Models from Liver Slice Experiments: What Are the Experimental Needs?

A mechanistic model is presented describing the clearance of a compound in a precision-cut liver slice that is incubated in a culture medium. The problem of estimating metabolic rate constants in PBPK models from liver slice experiments is discussed using identifiability analysis. From the identifiability problem analysis, it appears that in addition to the clearance, the compound's free fraction in the slice and the diffusion rate of the exchange of the compound between culture medium and liver slice should be identified. In addition, knowledge of the culture medium volume, the slice volume, the compound's free fraction, and octanol-water-based partition between medium and slice is presupposed. The formal solution for identification is discussed from the perspective of experimental practice. A formally necessary condition for identification is the sampling of parent compound in liver slice or culture medium. However, due to experimental limitations and errors, sampling the parent compound in the slice together with additional sampling of metabolite pooled from the medium and the slice is required for identification in practice. Moreover, it appears that identification results are unreliable when the value of the intrinsic clearance exceeds the value of the diffusion coefficient, a condition to be verified a posteriori.     

Influence diagnostics and outlier tests for semiparametric mixed models

Summary. Semiparametric mixed models are useful in biometric and econometric applications, especially for longitudinal data. Maximum penalized likelihood estimators (MPLEs) have been shown to work well by Zhang and co-workers for both linear coefficients and nonparametric functions. This paper considers the role of influence diagnostics in the MPLE by extending the case deletion and subject deletion analysis of linear models to accommodate the inclusion of a nonparametric component. We focus on influence measures for the fixed effects and provide formulae that are analogous to those for simpler models and readily computable with the MPLE algorithm. We also establish an equivalence between the case or subject deletion model and a mean shift outlier model from which we derive tests for outliers. The influence diagnostics proposed are illustrated through a longitudinal hormone study on progesterone and a simulated example.     

对网络教学的分析和探讨

随着知识经济的发展 ,网络已经日渐走入人们的生活并且开始显示其重要性。同时 ,社会对教育模式、教育手段都提出了新的要求。网络教学作为一种新型的教育方式 ,在我国迅速发展起来 ,并且成为远程教育的重要形式之一。本文就网络教学的学习理论、特点、定位以及现阶段我国网络教学与发达国家网络教学的差距进行了分析和探讨 ,并对我国网络教学今后的发展方向和需要解决的问题 ,提出了个人的见解。     

Internet与未来教育

Internet是20世纪末世界上最激动人心的发现,它将我们带入了一个完全信息化的时代,它正在改变着人们的生活和工作方式,也必将对中国未来教育发生深远的影响。从教育的内容、教育的方式方法、教育的观念等诸方面阐述了Internet对未来教育的影响,分析了未来教育将向着终身化、远程化和多媒体化、大众化、个性化、产业化和市场化等方向发展的趋势,同时提出了我们应采取的对策。