D-efficient window experimental designs

In the paper we present a new method of calculating sampling intervals, so-called windows, allowing an experimenter some flexibility in timing the sample collection, while a minimum required design efficiency for parameter estimation is assured. The method is based on the Equivalence Theorem for D-optimality what makes the length of each window related to the parameter sensitivities. An example of calculating the windows in a pharmacokinetic study is presented. Some other methods of calculating efficient sampling windows are briefly discussed.     

Improved approaches to interval estimation of effective doses for a logistic dose-response curve

Asymptotic confidence (delta) intervals and intervals based upon the use of Fieller's theorem are alternative methods for constructing intervals for the <$>\gamma<$>% effective doses (ED<$>_\gamma<$>). Sitter and Wu (1993) provided a comparison of the two approaches for the ED<$>_{50}<$>, for the case in which a logistic dose response curve is assumed. They showed that the Fieller intervals are generally superior. In this paper, we introduce two new families of intervals, both of which include the delta and Fieller intervals as special cases. In addition we consider interval estimation of the ED<$>_{90}<$> as well as the ED<$>_{50}<$>. We provide a comparison of the various methods for the problem of constructing a confidence interval for the ED<$>_\gamma<$>.     

A surplus process involving a compound Poisson counting process and applications

Abstract

In this paper, we introduce a surplus process involving a compound Poisson counting process, which is a generalization of the classical ruin model where the claim-counting process is a homogeneous Poisson process. The incentive is to model batch arrival of claims using a counting process that is based on a compound distribution. This reduces the difficulty of modeling claim amounts and is consistent with industrial data. Recursive formula, some properties and relevant main ruin theory results are provided. Further, we consider applications involving zero-truncated negative binomial and zero-truncated binomial batch arrivals when the claim amounts follow exponential or Erlang distribution.     

关于含参变量无穷积分的绝对一致收敛的注记

本文从一个反例 ,证明了即使∫∞af(x ,t)dt绝对收敛且一致收敛 ,但不能推出∫∞a |f(x ,t) |dt一致收敛。     

科斯定理与国家理论——权力、可信承诺与政治企业家

权力与可信承诺是国家理论的核心问题。引入权力因素导致科斯定理不再成立:在交易成本为零时,权力的不可转让性消除了趋向最优谈判的压力;而有限承诺加大了谈判结果偏离帕累托最优效率的程度。因此,为了有助于理解经济增长和制度变迁的国家理论,需要分析那些拥有权力的个体的行为。这些人包括专制国家中的君主以及民主国家中的政治家和官僚等。在经济增长和制度变迁过程中,他们中的一些人扮演着政治企业家的角色,发挥着关键行动者和“第一行动集团”的作用。权力和可信承诺是政治企业家理论的重要构成要素,对于把握政治企业家和制度变迁的关系具有重要意义。     

Maximal Invariant and Weakly Equivariant Estimators

Equivariant functions can be useful for constructing of maximal invariant statistic. In this article, we discuss construction of maximal invariants based on a given weakly equivariant function under some additional conditions. The theory easily extends to the case of two or more weakly equivariant functions. Also, we derive a maximal invariant statistic when the group contains a sharply transitive and a characteristic subgroup. Finally, we consider the independence of invariant and weakly equivariant functions under some special conditions.     

Central Limit Theorem approximations for the number of runs in Markov-dependent binary sequences

We consider Markov-dependent binary sequences and study various types of success runs (overlapping, non-overlapping, exact, etc.) by examining additive functionals based on state visits and transitions in an appropriate Markov chain. We establish a multivariate Central Limit Theorem for the number of these types of runs and obtain its covariance matrix by means of the recurrent potential matrix of the Markov chain. Explicit expressions for the covariance matrix are given in the Bernoulli and a simple Markov-dependent case by expressing the recurrent potential matrix in terms of the stationary distribution and the mean transition times in the chain. We also obtain a multivariate Central Limit Theorem for the joint number of non-overlapping runs of various sizes and give its covariance matrix in explicit form for Markov dependent trials.     

高斯定理的理解与应用

文章论述了高斯定理源于库仑定律，依赖于场强叠加原理，场强通量与场线通量均遵从高斯定理；高斯面上的场强是其内外所考虑的电荷产生的合场强；构建体系高斯面，局部高斯面求解场强问题。     

高等教育"民营化"问题的经济学思考

高等教育在新形势下进行了一系列改革,呈现了"民营化"趋势.其间出现了两个新的问题,即规模扩大后资源如何重新配置和后勤社会化后管理责任如何重新划分.本文运用经济学原理,主要是"科斯定理",分析了"民办机制"和民办高校在解决这两个问题时的优势,并提出了相应的对策建议.     

Non-Normal Bivariate Distributions with Normal Marginals

The purpose of this note is to indicate that Fieller's Theorem can be expressed in the matrix formulation of the general linear model. The practical consequence is that one general computer program which can estimate the parameters and test the validity of a pertinent model, can also compute confidence limits for the ratios of any linear combinations of the parameters.