Bias and Variance of the Nonparametric MLE Under Length-Biased Censored Sampling: A Simulation Study

Abstract

In some applications, the available data suffer from several sampling problems related to loss of information. This typically happens in Survival Analysis, where models for truncation, censorship, and biasing have been proposed and widely investigated. In this work, we analyze by simulations the (finite sample) bias and variance of the nonparametric MLE under length-biasing and right-censorship, recently introduced by de Uńa-Álvarez [de Uńa-Álvarez, J. (2002a). Product-limit estimation for length-biased censored data. Test 11:109–125]. Comparison with the time-honoured Kaplan–Meier estimate for censored data is included.     

Comparing Nonparametric Estimators for Length-Biased Data

Length-biased data appear when sampling lifetimes by cross-section. Right-censoring may affect the sampled information due to time limitation in following-up, lost to follow-up cases, etc. In this article, we compare by simulations two alternative nonparametric estimators of the lifetime distribution function when the data are length-biased and right-censored. These estimates, recently introduced in the literature, are based on nonparametric maximum-likelihood and moment-based principles. It is shown that the relative benefits associated to each estimator depend on several factors, such as the shape of the underlying distribution, sample size, or censoring level.     

Length-biased,with-replacement sampling from an exponential finite population

In this article, we study a statistical model which features a finite population of exponentially distributed values and a length-biased, with-replacement sampling mechanism. This mechanism is such that units compete with one another for selection at each draw. It is shown how inference on a number of quantities can be performed using both frequentist and Bayesian strategies. A Monte Carlo study is used to assess the performance of the proposed point and interval estimators.