A simple procedure for the selection of significant effects

Summary.  Given a large number of test statistics, a small proportion of which represent departures from the relevant null hypothesis, a simple rule is given for choosing those statistics that are indicative of departure. It is based on fitting by moments a mixture model to the set of test statistics and then deriving an estimated likelihood ratio. Simulation suggests that the procedure has good properties when the departure from an overall null hypothesis is not too small.     

Computation of an efficient and robust estimator in a semiparametric mixture model

In this article, we propose an efficient and robust estimation for the semiparametric mixture model that is a mixture of unknown location-shifted symmetric distributions. Our estimation is derived by minimizing the profile Hellinger distance (MPHD) between the model and a nonparametric density estimate. We propose a simple and efficient algorithm to find the proposed MPHD estimation. Monte Carlo simulation study is conducted to examine the finite sample performance of the proposed procedure and to compare it with other existing methods. Based on our empirical studies, the newly proposed procedure works very competitively compared to the existing methods for normal component cases and much better for non-normal component cases. More importantly, the proposed procedure is robust when the data are contaminated with outlying observations. A real data application is also provided to illustrate the proposed estimation procedure.     

Statistical estimation of internal available bandwidth

This paper presents a method for using end-to-end available bandwidth measurements in order to estimate available bandwidth on individual internal links. The basic approach is to use a power transform on the observed end-to-end measurements, model the result as a mixture of spatially correlated exponential random variables, carryout estimation by moment methods, then transform back to the original variables to get estimates and confidence intervals for the expected available bandwidth on each link. Because spatial dependence leads to certain parameter confounding, only upper bounds can be found reliably. Simulations with ns2 show that the method can work well and that the assumptions are approximately valid in the examples.     

Macro-Economic Factors in Credit Risk Calculations: Including Time-Varying Covariates in Mixture Cure Models

The prediction of the time of default in a credit risk setting via survival analysis needs to take a high censoring rate into account. This rate is because default does not occur for the majority of debtors. Mixture cure models allow the part of the loan population that is unsusceptible to default to be modeled, distinct from time of default for the susceptible population. In this article, we extend the mixture cure model to include time-varying covariates. We illustrate the method via simulations and by incorporating macro-economic factors as predictors for an actual bank dataset.     

Cytometry inference through adaptive atomic deconvolution

In this paper, we consider a statistical estimation problem known as atomic deconvolution. Introduced in reliability, this model has a direct application when considering biological data produced by flow cytometers. From a statistical point of view, we aim at inferring the percentage of cells expressing the selected molecule and the probability distribution function associated with its fluorescence emission. We propose here an adaptive estimation procedure based on a previous deconvolution procedure introduced by Es, Gugushvili, and Spreij [(2008), ‘Deconvolution for an atomic distribution’, Electronic Journal of Statistics, 2, 265–297] and Gugushvili, Es, and Spreij [(2011), ‘Deconvolution for an atomic distribution: rates of convergence’, Journal of Nonparametric Statistics, 23, 1003–1029]. For both estimating the mixing parameter and the mixing density automatically, we use the Lepskii method based on the optimal choice of a bandwidth using a bias-variance decomposition. We then derive some convergence rates that are shown to be minimax optimal (up to some log terms) in Sobolev classes. Finally, we apply our algorithm on the simulated and real biological data.     

Invariant co-ordinate selection

Summary.  A general method for exploring multivariate data by comparing different estimates of multivariate scatter is presented. The method is based on the eigenvalue–eigenvector decomposition of one scatter matrix relative to another. In particular, it is shown that the eigenvectors can be used to generate an affine invariant co-ordinate system for the multivariate data. Consequently, we view this method as a method for invariant co-ordinate selection . By plotting the data with respect to this new invariant co-ordinate system, various data structures can be revealed. For example, under certain independent components models, it is shown that the invariant co- ordinates correspond to the independent components. Another example pertains to mixtures of elliptical distributions. In this case, it is shown that a subset of the invariant co-ordinates corresponds to Fisher's linear discriminant subspace, even though the class identifications of the data points are unknown. Some illustrative examples are given.     

The generalized log-gamma mixture model with covariates: local influence and residual analysis

In a sample of censored survival times, the presence of an immune proportion of individuals who are not subject to death, failure or relapse, may be indicated by a relatively high number of individuals with large censored survival times. In this paper the generalized log-gamma model is modified for the possibility that long-term survivors may be present in the data. The model attempts to separately estimate the effects of covariates on the surviving fraction, that is, the proportion of the population for which the event never occurs. The logistic function is used for the regression model of the surviving fraction. Inference for the model parameters is considered via maximum likelihood. Some influence methods, such as the local influence and total local influence of an individual are derived, analyzed and discussed. Finally, a data set from the medical area is analyzed under the log-gamma generalized mixture model. A residual analysis is performed in order to select an appropriate model. The authors would like to thank the editor and referees for their helpful comments. This work was supported by CNPq, Brazil.     

Order statistics from trivariate normal and -distributions in terms of generalized skew-normal and skew- distributions

We consider here a generalization of the skew-normal distribution, GSN(λ₁,λ₂,ρ), defined through a standard bivariate normal distribution with correlation ρ, which is a special case of the unified multivariate skew-normal distribution studied recently by Arellano-Valle and Azzalini [2006. On the unification of families of skew-normal distributions. Scand. J. Statist. 33, 561–574]. We then present some simple and useful properties of this distribution and also derive its moment generating function in an explicit form. Next, we show that distributions of order statistics from the trivariate normal distribution are mixtures of these generalized skew-normal distributions; thence, using the established properties of the generalized skew-normal distribution, we derive the moment generating functions of order statistics, and also present expressions for means and variances of these order statistics.Next, we introduce a generalized skew-t_ν distribution, which is a special case of the unified multivariate skew-elliptical distribution presented by Arellano-Valle and Azzalini [2006. On the unification of families of skew-normal distributions. Scand. J. Statist. 33, 561–574] and is in fact a three-parameter generalization of Azzalini and Capitanio's [2003. Distributions generated by perturbation of symmetry with emphasis on a multivariate skew t distribution. J. Roy. Statist. Soc. Ser. B 65, 367–389] univariate skew-t_ν form. We then use the relationship between the generalized skew-normal and skew-t_ν distributions to discuss some properties of generalized skew-t_ν as well as distributions of order statistics from bivariate and trivariate t_ν distributions. We show that these distributions of order statistics are indeed mixtures of generalized skew-t_ν distributions, and then use this property to derive explicit expressions for means and variances of these order statistics.     

A comparison of nonparametric priors in hierarchical mixture modelling for AFT regression

We will pursue a Bayesian nonparametric approach in the hierarchical mixture modelling of lifetime data in two situations: density estimation, when the distribution is a mixture of parametric densities with a nonparametric mixing measure, and accelerated failure time (AFT) regression modelling, when the same type of mixture is used for the distribution of the error term. The Dirichlet process is a popular choice for the mixing measure, yielding a Dirichlet process mixture model for the error; as an alternative, we also allow the mixing measure to be equal to a normalized inverse-Gaussian prior, built from normalized inverse-Gaussian finite dimensional distributions, as recently proposed in the literature. Markov chain Monte Carlo techniques will be used to estimate the predictive distribution of the survival time, along with the posterior distribution of the regression parameters. A comparison between the two models will be carried out on the grounds of their predictive power and their ability to identify the number of components in a given mixture density.     

非线性面板数据聚类方法研究

对于一类变量非线性相关的面板数据,现有的基于线性算法的面板数据聚类方法并不能准确地度量样本间的相似性,且聚类结果的可解释性低。综合考虑变量非线性相关问题及聚类结果可解释性问题,提出一种非线性面板数据的聚类方法,通过非线性核主成分算法实现对样本相似性的测度,并基于混合高斯模型进行样本概率聚类,实证表明该方法的有效性及其对聚类结果的可解释性有所提高。