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1.
AbstractCharacterizing relations via Rényi entropy of m-generalized order statistics are considered along with examples and related stochastic orderings. Previous results for common order statistics are included. 相似文献
2.
Stephen J. Ruberg Frank E. Harrell Jr. Margaret Gamalo-Siebers Lisa LaVange J. Jack Lee Karen Price 《The American statistician》2019,73(1):319-327
ABSTRACTThe cost and time of pharmaceutical drug development continue to grow at rates that many say are unsustainable. These trends have enormous impact on what treatments get to patients, when they get them and how they are used. The statistical framework for supporting decisions in regulated clinical development of new medicines has followed a traditional path of frequentist methodology. Trials using hypothesis tests of “no treatment effect” are done routinely, and the p-value < 0.05 is often the determinant of what constitutes a “successful” trial. Many drugs fail in clinical development, adding to the cost of new medicines, and some evidence points blame at the deficiencies of the frequentist paradigm. An unknown number effective medicines may have been abandoned because trials were declared “unsuccessful” due to a p-value exceeding 0.05. Recently, the Bayesian paradigm has shown utility in the clinical drug development process for its probability-based inference. We argue for a Bayesian approach that employs data from other trials as a “prior” for Phase 3 trials so that synthesized evidence across trials can be utilized to compute probability statements that are valuable for understanding the magnitude of treatment effect. Such a Bayesian paradigm provides a promising framework for improving statistical inference and regulatory decision making. 相似文献
3.
Laurent Gardes Stéphane Girard Gilles Stupfler 《Scandinavian Journal of Statistics》2020,47(3):922-949
The conditional tail expectation (CTE) is an indicator of tail behavior that takes into account both the frequency and magnitude of a tail event. However, the asymptotic normality of its empirical estimator requires that the underlying distribution possess a finite variance; this can be a strong restriction in actuarial and financial applications. A valuable alternative is the median shortfall (MS), although it only gives information about the frequency of a tail event. We construct a class of tail Lp-medians encompassing the MS and CTE. For p in (1,2), a tail Lp-median depends on both the frequency and magnitude of tail events, and its empirical estimator is, within the range of the data, asymptotically normal under a condition weaker than a finite variance. We extrapolate this estimator and another technique to extreme levels using the heavy-tailed framework. The estimators are showcased on a simulation study and on real fire insurance data. 相似文献
4.
JOURNAL OF UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGY 2002 Vol.24 No.1~4 Total Contents 总被引:1,自引:0,他引:1
在学习英语时,中西文化背景的差异,往往会给我们的阅读带来很大的困难。本文拟从词汇的文化内涵、历史典故和西方现代历史文化等三个方面来论述中西文化差异对篇章阅读的影响。 相似文献
5.
Modelling daily multivariate pollutant data at multiple sites 总被引:7,自引:1,他引:6
Gavin Shaddick Jon Wakefield 《Journal of the Royal Statistical Society. Series C, Applied statistics》2002,51(3):351-372
Summary. This paper considers the spatiotemporal modelling of four pollutants measured daily at eight monitoring sites in London over a 4-year period. Such multiple-pollutant data sets measured over time at multiple sites within a region of interest are typical. Here, the modelling was carried out to provide the exposure for a study investigating the health effects of air pollution. Alternative objectives include the design problem of the positioning of a new monitoring site, or for regulatory purposes to determine whether environmental standards are being met. In general, analyses are hampered by missing data due, for example, to a particular pollutant not being measured at a site, a monitor being inactive by design (e.g. a 6-day monitoring schedule) or because of an unreliable or faulty monitor. Data of this type are modelled here within a dynamic linear modelling framework, in which the dependences across time, space and pollutants are exploited. Throughout the approach is Bayesian, with implementation via Markov chain Monte Carlo sampling. 相似文献
6.
Computing maximum likelihood estimates from type II doubly censored exponential data 总被引:1,自引:0,他引:1
Arturo J. fernández José I. Bravo Íñigo De Fuentes 《Statistical Methods and Applications》2002,11(2):187-200
It is well-known that, under Type II double censoring, the maximum likelihood (ML) estimators of the location and scale parameters, θ and δ, of a twoparameter exponential distribution are linear functions
of the order statistics. In contrast, when θ is known, theML estimator of δ does not admit a closed form expression. It is shown, however, that theML estimator of the scale parameter exists and is unique. Moreover, it has good large-sample properties. In addition, sharp
lower and upper bounds for this estimator are provided, which can serve as starting points for iterative interpolation methods
such as regula falsi. Explicit expressions for the expected Fisher information and Cramér-Rao lower bound are also derived.
In the Bayesian context, assuming an inverted gamma prior on δ, the uniqueness, boundedness and asymptotics of the highest
posterior density estimator of δ can be deduced in a similar way. Finally, an illustrative example is included. 相似文献
7.
互联网与文化重构及社会分化 总被引:3,自引:0,他引:3
互联网的出现不仅丰富了文化的表现形式 ,而且丰富了文化的基础 ,丰富了人们对真理、理性、伦理等文化基本矛盾的认识。互联网作为一种新的文化形态主要不是依据理论的完整性 ,而是依靠它在传播过程中的文化张力来实现的。互联网的出现导致了文化的多元化 ,推动了个人主义 ,冲击了传统文化的主导地位 ,冲击了传统的主流媒体赖以存在的稳定的文化环境 ,冲击了主流文化推崇的文化价值和伦理价值体系。 相似文献
8.
非统计专业统计学教育刍议 总被引:1,自引:0,他引:1
针对非统计专业统计学教育目前存在的问题,阐述了提高对统计学重要性的认识是保证统计教学效果的前提;统计学教学环节的改革是提高教学效果的重要保证;统计教师的业务素质是提高统计教学效果的关键。 相似文献
9.
王瑞江 《中国地质大学学报(社会科学版)》2006,6(2):93-97
从人类实践活动、人类社会发展不同历史阶段时代背景、时代特征、时代要求和时代主题的差异性、马克思主义自身的理论品质、马克思主义政党及其政治领袖们关于理论建设的自觉性和创新精神等几个方面论述了马克思主义发展的动力机制。 相似文献
10.
The well-known chi-squared goodness-of-fit test for a multinomial distribution is generally biased when the observations are subject to misclassification. In Pardo and Zografos (2000) the problem was considered using a double sampling scheme and ø-divergence test statistics. A new problem appears if the null hypothesis is not simple because it is necessary to give estimators for the unknown parameters. In this paper the minimum ø-divergence estimators are considered and some of their properties are established. The proposed ø-divergence test statistics are obtained by calculating ø-divergences between probability density functions and by replacing parameters by their minimum ø-divergence estimators in the derived expressions. Asymptotic distributions of the new test statistics are also obtained. The testing procedure is illustrated with an example. 相似文献