Increased prevalence of premature ejaculation in men with metabolic syndrome

This prospective study aimed to investigate the relationship between metabolic syndrome (Met S) and premature ejaculation (PE) among men. The study included 300 consecutive male patients (53.6 y?±?8.7) who attended the urology clinic (December 2013–September 2014), mostly complaining of renal/ureteric calculi. A diagnostic approach was undertaken to include demographics, clinical features and laboratory investigations of the study subjects. Both erectile function and PE were evaluated using the International Index of Erectile Function (abridged form, IIEF-5) and Premature Ejaculation Diagnostic Tool (PEDT) questionnaires, respectively. Results identified 182 (60.7%) men had Met S. Prevalence of PE was significantly higher in the subjects with Met S than the controls (35.2% vs 7.6%, p?< 0.001). Patients with Met S and PE had significantly higher PEDT scores (15.4 vs 6.7), smaller waist circumference (108.3?cm vs 111.5?cm) and higher fasting blood sugar (187?mg% vs 161?mg%) than those with no PE (p?p?=?0.047 and <0.001, respectively) with PE in Met S. In conclusion, PE has a high prevalence in Met S. Patients with Met S should be questioned about PE. Both ED and systolic hypertension may be associated with PE. Prevention of Met S should be considered, and this may be of help to decrease the prevalence of PE.     

Semiparametric regression methods for temporal processes subject to multiple sources of censoring

Process regression methodology is underdeveloped relative to the frequency with which pertinent data arise. In this article, the response-190 is a binary indicator process representing the joint event of being alive and remaining in a specific state. The process is indexed by time (e.g., time since diagnosis) and observed continuously. Data of this sort occur frequently in the study of chronic disease. A general area of application involves a recurrent event with non-negligible duration (e.g., hospitalization and associated length of hospital stay) and subject to a terminating event (e.g., death). We propose a semiparametric multiplicative model for the process version of the probability of being alive and in the (transient) state of interest. Under the proposed methods, the regression parameter is estimated through a procedure that does not require estimating the baseline probability. Unlike the majority of process regression methods, the proposed methods accommodate multiple sources of censoring. In particular, we derive a computationally convenient variant of inverse probability of censoring weighting based on the additive hazards model. We show that the regression parameter estimator is asymptotically normal, and that the baseline probability function estimator converges to a Gaussian process. Simulations demonstrate that our estimators have good finite sample performance. We apply our method to national end-stage liver disease data. The Canadian Journal of Statistics 48: 222–237; 2020 © 2019 Statistical Society of Canada     

Prevalence of low bone health using quantitative ultrasound in Indian women aged 41–60 years: Its association with nutrition and other related risk factors

The purpose of this study was to find the prevalence of low bone health conditions and assess associated nutritional and other risk factors in Indian women aged 41–60 years. A total of 1,911 women participated in this cross-sectional study. Bone health was assessed using an Omnisense multisite quantitative ultrasound bone densitometer on two sites (radius and tibia). Crude prevalence of osteopenia and osteoporosis was found to be 30.09% and 19.89%, respectively. The Indian women were deficient in a majority of nutrients. Postmenopause, hysterectomy, hyperthyroid, hypothyroid, hypertension, low physical activity, low sun exposure, high stress levels, and low calcium levels were found to be independent risk factors of low bone health.     

Workplace aggression against health care workers,law enforcement officials,and bus drivers: Differences in prevalence,perceptions, and psychological consequences

Investigations into workplace aggression (WPA) remain largely occupation specific, with few studies using a comparative approach. The aim of the present study was to compare the health care, law enforcement, and public transportation sectors with regards to the prevalence of different types of WPA, the perceptions of workers toward WPA, and the psychological consequences of such acts. A cross-sectional survey was completed by 1,774 workers in Canada. Multinomial regressions were utilized to address the objectives. Findings revealed that verbal abuse victimization was particularly common in bus drivers, witnessing death threats was most frequent among law enforcement officials, and witnessing all types of WPA was most common among health care workers. Although bus drivers did not normalize WPA, they feared complaining about violence to their employer and thought it useless to talk it about unless wounds were visible. Fear of complaining about violence to colleagues was prevalent in health care and law enforcement, both sectors in which WPA was normalized. Finally, flashbacks and irritability following WPA were most likely to affect bus drivers whereas health care workers experienced hypervigilance to a greater extent. Strategies to tailor primary, secondary, and tertiary prevention according to these distinctions are suggested to offer a better-informed response to WPA.     

Prevalence,incidence and risk factors of testosterone deficiency in a population-based cohort of men: results from the study of health in Pomerania

Objective.?Low total testosterone levels (TT) have been associated with increased morbidity and mortality. However, the prevalence and incidence of testosterone deficiency (TD) in association with its risk has not been assessed systematically to date.

Methods.?Data from the prospective population-based Study of Health in Pomerania were used. From the 2117 men aged 20–79 years at baseline, 1490 men with complete TT data were analysed. Crude and age-specific prevalence and incidence rates of TD were estimated by TT levels below the age-specific 10th percentile. Analysis of covariance and Poisson regression models were used to assess the association of socio-demographic characteristics, health-related lifestyle, as well as somatometric, medical and laboratory measures with risk of incident TD.

Results.?TD baseline prevalence was 10.4% (N?=?155) and incidence 11.7 per 1000 person-years. TT levels showed a significant age-related decline with an unadjusted rate of 0.05 nmol/l per year. Obesity, metabolic syndrome, diabetes and dyslipidaemia were identified as risk factors of incident TD. Subpopulations of men without the revealed risk factors at both examinations maintained constant TT levels over time.

Conclusions.?Besides aging alone, lifestyle and different comorbidities were associated with TT level decline, suggesting that the age-related TT decline may be at least partly prevented through the management of potentially modifiable risk factors and health related behaviour.     

Prevalence Rates of Youth Gambling Problems: Are the Current Rates Inflated?

While there is a general consensus in the literature that it is common for youth to gamble, considerable variability in the reported prevalence rates of youth problem gambling has been found. More recently, issues concerning the possible overestimation of these rates have been raised. Arguments underlying the proposition that problem gambling rates for youth are inflated are examined. It is acknowledged that more rigorous research is required, including the need for the development and refinement of current adolescent instruments and screening tools, agreement upon a gold standard criterion for adolescent problem gambling, and clarity of nomenclature issues. The advancement of scientific knowledge concerning the underlying risk factors associated with the onset and course of youth gambling involvement and the role of effective adolescent prevention and treatment programs will require these fundamental research questions to be addressed.     

Using repeated-prevalence data in multi-state modeling of renal replacement therapy

Multi-state models help predict future numbers of patients requiring specific treatments but these models require exhaustive incidence data. Deriving reliable predictions from repeated-prevalence data would be helpful. A new method to model the number of patients that switch between therapeutic modalities using repeated-prevalence data is presented and illustrated. The parameters and goodness of fit obtained with the new method and repeated-prevalence data were compared to those obtained with the classical method and incidence data. The multi-state model parameters’ confidence intervals obtained with annually collected repeated-prevalence data were wider than those obtained with incidence data and six out of nine pairs of confidence intervals did not overlap. However, most parameters were of the same order of magnitude and the predicted patient distributions among various renal replacement therapies were similar regardless of the type of data used. In the absence of incidence data, a multi-state model can still be successfully built with annually collected repeated-prevalence data to predict the numbers of patients requiring specific treatments. This modeling technique can be extended to other chronic diseases.     

商业贿赂泛盛机理及对策

商业贿赂是随着商品经济的发展而发展起来的一种经济现象.随着我国市场经济的发展,商业贿赂现象在我国已经达到泛滥的程度.目前,我国已经将治理商业贿赂放在一个非常重要的地位.商业贿赂泛盛机理主要体现在:市场主体的趋利性是商业贿赂存在的前提条件;法制不健全助长了商业贿赂的泛盛;执法体制不顺使商业贿赂得不到应有的惩治;一些行业已形成的"潜规则",给惩治商业贿赂行为带来了难度.治理我国商业贿赂行为的对策,主要包括:构建反商业贿赂的法律体系;设置防范机制,遏制商业贿赂;完善举报制度;转变政府职能,减少权力寻租机会;建立和完善职业道德,加强行业自律;营造健康的商业文化等.     

Estimating the Prevalence of Illegal Drug Use

A generic globally applicable integral equation allows the estimation of hidden drug use. Formulas for estimating the prevalence of drug use are provided for both the assumed and known latency period. Estimates of prevalence of opiate use in Ireland ranging from 7,955 [5,789, 10,122] to 11,986 [8,792, 15,181] with prevalence rates ranging from 2.7 [2.0, 3.5] per 1,000 to 4.1 [3.0, 5.2] were obtained. The model can be implemented by service providers and planners if numbers of first treatments for drug use and the latency period are known or assumed.     

Smoking Prevalence and Antismoking Regulations in Transition Countries

As a number of new nations emerged in the early nineties, there has been a spurt in regulatory initiatives in transition countries toward nation building and socio-economic reforms. A key prerequisite to policy changes is an understanding of the related patterns and policies. This paper provides an overview of the smoking trends in transition nations, broken by gender and age, and the antismoking policies in place. In particular, four different types of non-price policies are studied. Comparisons with the rest of the world show that transition countries do not fare badly in terms of implementing antismoking policies and are, in fact, better in some cases than other countries. However, greater smoking prevalence for some population subgroups in transition nations suggests that either some other socio-economic factors influencing smoking prevalence might be at play or there might be some enforcement issues with the policies in place.