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Non‐parametric Bayesian Intensity Model: Exploring Time‐to‐Event Data on Two Time Scales
Authors:Tommi Härkänen  Anna But  Jari Haukka
Institution:1. Department of Public Health SolutionsNational Institute for Health and Welfare;2. Department of Public HealthUniversity of Helsinki
Abstract:Time‐to‐event data have been extensively studied in many areas. Although multiple time scales are often observed, commonly used methods are based on a single time scale. Analysing time‐to‐event data on two time scales can offer a more extensive insight into the phenomenon. We introduce a non‐parametric Bayesian intensity model to analyse two‐dimensional point process on Lexis diagrams. After a simple discretization of the two‐dimensional process, we model the intensity by a one‐dimensional piecewise constant hazard functions parametrized by the change points and corresponding hazard levels. Our prior distribution incorporates a built‐in smoothing feature in two dimensions. We implement posterior simulation using the reversible jump Metropolis–Hastings algorithm and demonstrate the applicability of the method using both simulated and empirical survival data. Our approach outperforms commonly applied models by borrowing strength in two dimensions.
Keywords:event history  hazard rate  intensity function  Lexis diagram  Poisson process  reversible jump MCMC  smoothing  survival analysis  two‐dimensional
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