Abstract: | In many experimental situations, d-way heterogeneity among experimental units may be controlled through use of multiple blocking criteria. In some cases it is reasonable to regard some or all of the block effects as random. Then the model is mixed and observations within blocks are correlated. Very general estimators of treatment effects and their dispersion matrix with recovery of interblock information are provided. They apply to designs with d > 1 blocking criteria that may be crossed, nested, or a combination thereof. These general results may be specialized to provide analyses of new classes of MBD's or used directly for numerical analyses of designs in the general class, perhaps through use as the basis for very general computer programs. Estimation of variance components is discussed, and an example is provided to illustrate adaptation of the general results. |