进展性缺血性脑卒中临床预后因素的分析

目的观察急性脑梗死患者血清钙（Ca2＋）、神经元特异性烯醇化酶（NSE）、超敏C反应蛋白（hs-CRP）的含量变化,探讨对急性脑梗死患者临床预后的影响。方法根据病情将病例组分为进展性脑梗死组和对照组。检测131例进展性脑梗死患者和131例对照组患者早期血清Ca2＋、NSE、hs-CRP含量。结果进展性脑梗死组与对照组比较血清Ca2＋含量显著减少（P〈0.01）,血清NSE、hs-CRP含量显著增加（P〈0.01）。结论血清Ca2＋、NSE和hs-CRP含量的变化可作为评估病情进展的指标。

Analysis of influential factors on pronosis of progressive ischemic stroke

Objective To observe the changes of serum calcium,neuron-specific enolase （NSE） and hs-CRP levels in the patients with acute cerebral infarction and to discussion the effects on the clinical prognosis of patients with progressive ischemic stroke. Methods The patients were divided into progressive ischemic stroke group and control group. Use Roche MODULAR P-800 automatic biochemical analyzer and Roche E170 Chemiluminescence instrument to detect the serum of Ca^2＋,NSE and hs-CRP levels. Results Ca^2＋ levels were significanthy decreased （P〈0.01 compared to control group） and NSE,hs-CRP levels were significanthy increased （P〈0.01 compared to control group）in the progressive ischemic stroke group compared with control group. Conclusion The changes of serum levels of calcium,NSE and hs-CRP in acute cerebral infarction can be indicators to assess the progress of the disease.