首页 | 本学科首页   官方微博 | 高级检索  
     


Inherited frailty and longevity
Authors:James W Vaupel
Affiliation:Humphrey Institute of Public Affairs, University of Minnesota, Minneapolis 55455.
Abstract:The life spans of parents and children appear only weakly related, even though parents affect their children's longevity through both genetic and environmental influences. These influences can be summarized as a correlation between parents' and children's frailty. It is shown that even if children perfectly inherit their frailty from their parents, parents' life spans explain little of the variance in children's life spans, because the variance in life expectancies among people with different frailties is small compared with the variance in life spans among people at the same level of frailty. By interpreting frailty as a relative risk in a proportional-hazard model, longevity as a duration or waiting time, and inheritance as an invariance in relative risk over time, one can extend this result to repeatable events involving fertility, migration, marriage, unemployment, and so forth.
Keywords:
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号