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Nonparametric bootstrapping for hierarchical data
Authors:Shiquan Ren  Hong Lai  Wenjing Tong  Mostafa Aminzadeh  Xuezhang Hou  Shenghan Lai
Affiliation:1. School of Biological, Earth and Environmental Sciences , University of New South Wales , Sydney , Australia;2. Departments of Radiology and Pathology , Johns Hopkins University School of Medicine , Baltimore , USA;3. Mathematics Department of Towson University , Towson , USA
Abstract:Nonparametric bootstrapping for hierarchical data is relatively underdeveloped and not straightforward: certainly it does not make sense to use simple nonparametric resampling, which treats all observations as independent. We have provided some resampling strategies of hierarchical data, proved that the strategy of nonparametric bootstrapping on the highest level (randomly sampling all other levels without replacement within the highest level selected by randomly sampling the highest levels with replacement) is better than that on lower levels, analyzed real data and performed simulation studies.
Keywords:random effects model  hierarchical data  nonparametric bootstrapping  resampling schemes  unbalanced data
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