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Le Cam theorem on interval division by randomly chosen points: Pedagogical explanations and application to temporal cluster detection
Authors:Christophe  Demattei
Institution:Biostatistics, Epidemiology, Public Health and Medical Information Department , Nimes University Hospital Center , 30029 , Nimes , France
Abstract:The aim of this paper is to propose a pedagogical explanation of the Le Cam theorem and to illustrate its use, through a practical application, for temporal cluster detection. This theorem focusses on the interval division by randomly chosen points. The aim of the theorem is to characterize the asymptotic behavior of a certain category of sums of functions applied to the length of successive intervals between points. It is not very intuitive and its understanding needs some deepening. After enouncing the theorem, its different aspects are explained and detailed in a way as pedagogical as possible. Theoretical applications are proposed through the proof of two propositions. Then a very concrete application of this theorem for temporal cluster detection is presented, tested by a power study, and compared with other global cluster detection tests. Finally, this approach is applied to the well-known Knox temporal data set.
Keywords:Le Cam theorem  uniform spacings  cluster detection  temporal cluster  Knox data set
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