| 不同化疗方案治疗晚期胃癌的疗效观察 |
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| 引用本文： | 尹必俭,刘德林,陆建伟,冯继锋.不同化疗方案治疗晚期胃癌的疗效观察[J].西南科技大学学报(哲学社会科学版),2009,7(4):36-38. |
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| 作者姓名： | 尹必俭 刘德林 陆建伟 冯继锋 |
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| 作者单位： | 江苏省肿瘤医院,内科,210009 |
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| 摘 要： | 目的比较FOLFOX、CF、DCFZ种化疗方案治疗晚期胃癌的效果。方法回顾分析173例分别采用FOLFOX、CF及DCF3种治疗方案的初治晚期胃癌患者：其中采用FOLFOX方案治疗71例，CF方案59例，DCF方案43例。每28天为1个疗程，至少完成2个周期的化疗后，评估患者的近期疗效和毒副反应。结果3种方案的近期疗效分别为：FOLFOX方案31．0％，CF方案27．1％，DCF方案55．8％，DCF方案疗效明显高于其他两个方案，差异有统计学意义（P〈0．01）。毒副反应主要为骨髓抑制和消化道反应，DCF方案发生几率较高，但患者均可耐受，差异无统计学意义（P〉0．05）。结论晚期胃癌患者应用DCF方案近期疗效较好，不良反应可以耐受，值得临床推广使用。
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| 关 键 词： | 晚期胃癌 化学治疗 多西他赛 氟脲嘧定 顺铂 |
Comparative study of different chemotherapy regimen in patients with advanced gastric cancer |
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| YIN Bijian,LIU Delin,LU Jianwei,FENG Jifeng.Comparative study of different chemotherapy regimen in patients with advanced gastric cancer[J].Journal of Southwest University of Science and Technology,2009,7(4):36-38. |
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| Authors: | YIN Bijian LIU Delin LU Jianwei FENG Jifeng |
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| Institution: | YIN Bijian,LIU Delin,LU Jianwei,FENG Jifeng. Department of Oncology,Jiang Su Cancer Hospital,Nanjing,Jiangsu 210009,China. |
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| Abstract: | Objective Different chemotherapy regimen in patients with advanced gastric cancer were been compared on the clinical effect. Methods 173 patients with advanced gastric cancer were Divided into 3 groups,and each group patients were treated By different chemotherapy regimen,FOLFOX,CF or DCF. Curative effect and adverse reaction were compared among the patients of these three groups after 2 cycles' chemotherapy. Results The short-term response rate of 3 group were 31.0% ,27.1% and 55.8% respectively. DCF regim... |
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| Keywords: | Advanced gastric cancer Chemotherapy regiman Docetaxel Fluorouracil Cisplatin |
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