An assessment of the statistical methods used to analyse toxicology studies |
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| Authors: | Jarvis Philip Saul Jim Aylott Mike Bate Simon Geys Helena Sherington John |
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| Affiliation: | Discovery Statistics, AstraZeneca R&D, Alderley Park, Macclesfield, Cheshire, UK. Philip.Jarvis@AstraZeneca.com |
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| Abstract: | The Statisticians in the Pharmaceutical Industry Toxicology Special Interest Group has collated and compared statistical analysis methods for a number of toxicology study types including general toxicology, genetic toxicology, safety pharmacology and carcinogenicity. In this paper, we present the study design, experimental units and analysis methods. |
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