| 脑室注射6-羟基多巴胺对兔瞬膜条件反射的影响 |
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| 引用本文： | 王坚. 脑室注射6-羟基多巴胺对兔瞬膜条件反射的影响[J]. 苏州科技学院学报(社会科学版), 1992, 0(Z4) |
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| 作者姓名： | 王坚 |
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| 作者单位： | 铁道师院生物系 |
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| 摘 要： | 兔瞬膜条件反射是以声音结合电刺激瞬膜建立起来的条件反射。本文观察了侧脑室注射6-羟基多巴胺(6-OHDA)对兔瞬膜条件反射的影响。结果表明:侧脑室注射6-OHDA可延缓瞬膜条件反射的建立,但非条件反射一直存在,6-OHDA对巩固后的条件反射没有影响。这提示:儿茶酚胺类物质参与条件反射的获得及其巩固过程的调制,而对长期记忆没有影响。
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| 关 键 词： | 6-羟基多巴胺 瞬膜条件反射 学习 记忆 去甲肾上腺素 多巴胺 儿茶酚胺 |
Effects of Intraventricular Injection of 6-Hydroxydopamine on Classical Conditioning of the Rabbit Nictitating Membrane Response |
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| Wang Jian. Effects of Intraventricular Injection of 6-Hydroxydopamine on Classical Conditioning of the Rabbit Nictitating Membrane Response[J]. Journal of University of Science and Technology of Suzhou:Social Science, 1992, 0(Z4) |
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| Authors: | Wang Jian |
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| Affiliation: | Deportment of Biology |
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| Abstract: | Classical conditioning of the rabbit nictitating membrane response was accomplished by standard delay procedure of paired tone ( CS ) and electric ( US ) stimulus. Effects of intraventricular injection of 6-hydro-xydopamine ( 6-OHDA ) on nictitating membrane conditioning were investigated. It was observed that intraventricular injection of 6-OHDA caused suppression of nictitating membrane conditioning without affecting the unconditioned nictitating membrane response. These findings suggested that ca-techolamine ( CA ) played a modulatory role in the processes of acquisition and consolidation of conditioned reflex, but had no significant effect on long term memory. |
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| Keywords: | 6-hydroxydopamine nictitating membrane conditioning learning memory catecholamine noradrenaline dopamine |
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