| 尿微量白蛋白、超敏C反应蛋白和低密度脂蛋白胆固醇在糖尿病肾病检测中的意义 |
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| 引用本文： | 张丽娟,赖家盈,舒晓春.尿微量白蛋白、超敏C反应蛋白和低密度脂蛋白胆固醇在糖尿病肾病检测中的意义[J].西南科技大学学报(哲学社会科学版),2011,9(4). |
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| 作者姓名： | 张丽娟 赖家盈 舒晓春 |
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| 作者单位： | 中山大学附属第五医院,检验科,519000 |
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| 摘 要： | 目的 探讨尿微量白蛋白(mALB)、超敏C反应蛋白(hsCRP)和低密度脂蛋白胆固醇(LDL-C)与糖尿病肾病(diabetic nephropathy,DN)的关系.方法 测定185例DN患者的mALB、hsCRP、LDL-C水平,根据尿白蛋白排泄率分为正常蛋白尿组、微量白蛋白尿组、临床蛋白尿组,统计各组尿mALB、hsCRP、LDL-C水平;以100例健康检查者为对照组.结果 DN各组尿mALB、hsCRP、LDL-C水平均高于对照组,DN各组hsCRP、尿mALB水平有显著差异(P<0.05).结论 hsCRP、尿mALB和LDL-C与2型糖尿病肾病的发生、发展有密切联系;hsCRP和尿mALB在早期诊断DN方面优于LDL-C.
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| 关 键 词： | 糖尿病肾病 超敏C反应蛋白 尿微量白蛋白 低密度脂蛋白胆固醇 |
Significance of detection of urinary microalbuminuria,serum high sensitive C-reactive protein and low-density lipoprotein cholesterol in diabetic nephropathy |
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| ZHANG Lijuan,LAI Jiaying,SHU Xiaochun.Significance of detection of urinary microalbuminuria,serum high sensitive C-reactive protein and low-density lipoprotein cholesterol in diabetic nephropathy[J].Journal of Southwest University of Science and Technology,2011,9(4). |
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| Authors: | ZHANG Lijuan LAI Jiaying SHU Xiaochun |
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| Institution: | ZHANG Lijuan,LAI Jiaying,SHU Xiaochun.Department of Clinical Laboratoy,The Fifth Affiliated Hospital of Sun Yat-sen University,Guangdong Zhuhai 519000,China |
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| Abstract: | Objective To investigate the relationship of urinary microalbumin (mALB), serum high sensitive C-reactive protein (hsCRP) and low density lipoprotein cholesterol (LDL-C) levels with diabetic nephropathy (diabetic nephropathy, DN). Methods 185 patients with DN were determined mALB, hsCRP, LDL-C levels, according to urinary albumin excretion rate were divided into normal albuminuria group and microalbuminuria group, clinical proteinuria group, statistics of each group of urine mALB, hsCRP, LDLC levels; 100 he... |
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| Keywords: | Diabetic nephropathy high sensitivity C-reactive protein urinary microalbuminuria low-density lipoprotein cholesterol |
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