Markov chain Monte Carlo methods for family trees using a parallel processor |
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| Authors: | Russell Bradford Alun Thomas |
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| Institution: | (1) School of Mathematical Sciences, University of Bath, BA2 7AY Bath, UK;(2) Myriad Genetics, 390 Wakara Way, 84108 Salt Lake City, Utah, USA |
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| Abstract: | A 1024 CPU parallel computer is used to obtain simulated genotypes in the Tristan da Cunha pedigree using random local updating methods. A four-colour theorem is invoked to justify simultaneous updating. Multiple copies of the program are run simultaneously. These results are used to infer the source of the B allele of the ABO blood group that is present in the population. |
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| Keywords: | Ancestral inference Gibbs sampling massively parallel pedigree analysis |
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