| 炎症性肠病免疫学研究进展 |
| |
| 引用本文： | 高云峰,蔡红慧.炎症性肠病免疫学研究进展[J].绍兴文理学院学报,2003,23(8):22-24. |
| |
| 作者姓名： | 高云峰 蔡红慧 |
| |
| 作者单位： | 绍兴文理学院,医学院,浙江,绍兴,312000 |
| |
| 摘 要： | 炎症性肠病是一组病因未明的慢性肠道炎症性疾病，多以腹痛与腹泻为主要肠道症状．近年来人们发现其病因包括多种因素，其中与机体的免疫系统有明显关系．患的HLA—DR1、HLA—DQw5明显增高；肠粘膜免疫细胞散量增多，肠局部体液或细胞免疫活性增强、多数UC患P—ANCA阳性；TH1/TH2失衡；以及在IBD初期，内皮细胞表达ICAM-1明显增加．
|
| 关 键 词： | 炎症性肠病 免疫学 研究进展 腹痛 腹泻 免疫系统 免疫活性 发病机制 |
| 文章编号： | 1008-293X(2003)08-0022-03 |
| 修稿时间： | 2002年12月20 |
Advances in Immunology Studies of Inflammatory Bowel Disease |
| |
| Gao Yunfeng Cai Honghui.Advances in Immunology Studies of Inflammatory Bowel Disease[J].Journal of Shaoxing College of Arts and Sciences,2003,23(8):22-24. |
| |
| Authors: | Gao Yunfeng Cai Honghui |
| |
| Abstract: | Inflammatory bowel disease (IBD) is a group of chronic intestinal inflammatory diseases with main symptom of abdominal pain and diarrhea, the cause of which is not clear up till now. There are many factors found by researchers recently in the development of IBD, one of which is related to immune system of human body. In patients of IBD, HLA - DR1 and HLA - DQW5 rise, immunocytes number of intestinal mucous membrane increases, and intestinal local humor and cellular immune competence grow. P - ANCA of most UC patients is positive, TH1/TH2 is imbal-anced and ICAM - 1 expression of endotheliumcytes increases significantly. |
| |
| Keywords: | inflammatory bowel disease immunity antigen |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
