Bayesian estimation and stochastic model specification search for dynamic survival models

Dynamic survival models are a useful extension of the popular Cox model as the effects of explanatory variables are allowed to change over time. In this paper a new auxiliary mixture sampler for Bayesian estimation of the model parameters is introduced. This sampler forms the basis of a model space MCMC method for stochastic model specification search in dynamic survival models, which involves selection of covariates to include in the model as well as specification of effects as time-varying or constant. The method is applied to two well-known data sets from the literature.