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Corporate corruption of medical literature: Asbestos studies concealed by W. R. Grace & Co.?
Authors:David Egilman  Wes Wallace  Candace Hom
Institution:1. Department of Community Health, Brown University , South Shore Health Center , 759 Granite Street, Braintree, MA, 02184;2. South Shore Health Center , 759 Granite Street, Braintree, MA, 02184
Abstract:

In 1959, an X‐ray survey of 130 mine workers in Libby, Montana found that 48 had evidence of asbestos‐related lung disease. The ore they were mining contained up to 30% tremolite, an asbestiform mineral. In 1963, W.R. Grace acquired the mine and employee health problems at the mine became known to W.R. Grace executives and to Grace's insurance company, Maryland Casualty. In 1976, in response to tighter federal regulation of asbestos and asbestos‐containing products, W.R. Grace funded an animal study of tremolite toxicity. They hoped to prove that tremolite did not cause mesothelioma, the cancer uniquely associated with asbestos exposure. However, the study showed that tremolite did cause mesothelioma. W.R. Grace never disclosed the results of this animal study, nor did they disclose their knowledge of lung disease in the Libby workers, either to the workers themselves or to regulatory agencies. These actions were intentional, and were motivated by Grace's conscious decision to prioritize corporate profit over human health.
Keywords:Mesothelioma  tremolite  vermiculite  nondisclosure agreement  scientific misconduct  ethics
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