Practical guide to sample size calculations: an introduction |
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| Authors: | Laura Flight Steven A Julious |
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| Institution: | Medical Statistics Group, University of Sheffield, Sheffield, England |
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| Abstract: | A sample size justification is a vital step when designing any trial. However, estimating the number of participants required to give a meaningful result is not always straightforward. A number of components are required to facilitate a suitable sample size calculation. In this paper, the general steps are summarised for conducting sample size calculations with practical advice and guidance on how to utilise the app SampSize. Copyright © 2015 John Wiley & Sons, Ltd. |
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| Keywords: | sample size superiority non‐inferiority equivalence power clinical trials |
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