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On the influence curve for quantal bioassay
Authors:Barry R James  Kang Ling James
Institution:Instituto de Mathemática Pura e Aplicada (IMPA), Rio de Janeiro, Brazil
Abstract:Influence curves are defined for estimators of the ED50 in quantal bioassay, assuming a symmetic tolerance distribution. A definition of influence-curve robustness is suggested. Influence curves are obtained for L-,M- and R-estimators, and their robustness is investigated. The influence curve of the logistic maximum likelihood estimator is studied.
Keywords:Primary 62G05  62P10  Secondary 62G35  Quantal bioassay  Median effective dose  Influence curve  Robust estimators
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