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自体角膜缘干细胞移植联合丝裂霉C、逆行性翼状胬肉切除术的疗效观察
引用本文:邵杰,刁路明.自体角膜缘干细胞移植联合丝裂霉C、逆行性翼状胬肉切除术的疗效观察[J].西南科技大学学报(哲学社会科学版),2009,7(1):67-69.
作者姓名:邵杰  刁路明
作者单位:邵杰,SHAO Jie(湖北省武汉大学,基础医学院,430072;郧阳医学院附属十堰市人民医院,眼科,442000);刁路明,DIAO LuMing(湖北省武汉大学,基础医学院,430072)  
摘    要:目的探讨逆行性翼状胬肉切除、自体角膜缘干细胞移植联合丝裂霉素C治疗翼状胬肉的临床效果和安全性。方法选取69例(76眼)翼状胬肉患者,采用逆行性翼状胬肉切除、自体角膜缘干细胞移植联合丝裂霉素C进行治疗然后进行随访观察。结果所有患者均接受了10—13.5月(平均12月)以上的随访,有3例患者复发,没有发现任何并发症。结论逆行性翼状胬肉切除、自体角膜缘干细胞移植联合丝裂霉素C治疗翼状胬肉是一种简便、安全有效的治疗方法。

关 键 词:翼状胬肉  移植  自体角膜缘干细胞  改良手术  丝裂霉素C

Effects of auto-corneal limbus stem cell transplantation combined with mitomycin ctreatment in the improved pterygium surgery
SHAO Jie,DIAO LuMing. Pathology Teaching Room,Preclinical Medical College of Wuhan University,Wuhan,China.Effects of auto-corneal limbus stem cell transplantation combined with mitomycin ctreatment in the improved pterygium surgery[J].Journal of Southwest University of Science and Technology,2009,7(1):67-69.
Authors:SHAO Jie    DIAO LuMing Pathology Teaching Room  Preclinical Medical College of Wuhan University  Wuhan    China
Institution:SHAO Jie1,2,DIAO LuMing1.1 Pathology Teaching Room,Preclinical Medical College of Wuhan University,Wuhan,430072,China.2 Department of Ophthalmology,People's Hospital of Yunyang medical college of Shiyan,Shiyan,442000,China.
Abstract:Objective To explore the clinical effect and safety of auto-corneal limbus stem cell transplantation combined with MMC in the treatment of improved pteryglum surgery.Methods 46 patients (50 eyes)with pterygium received improved pterygium excision operation.During the surgery,the entire pterygium was striped with corneal epithelium,bare sclera was exposed to 0.2g/L MMC for 2-3rain,the eyes were given auto-corneal limbus stem cell transplantation.Results All the cases were followed up for average 12 too.the pterygium recurrence appeared in two eyes and no serious complication were observed.Conclusion These findings suggest that in the pterygium improved surgey auto-corneal limbus stem cell transplantation combined with topical MMC can significantly decrease the recurrence rate of pterygium,and it is a convenient, safe and effective method.
Keywords:Pterygium  Transplantation  Auto-eomeallimbus stem cell  Improved surgery  MMC  
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