Psychological Aspects of Predictive Genetic-Test Decisions: What Do We Know So Far?

Advances in molecular biology are facilitating the elucidation of the genetic basis of disease at an astonishing rate. Consequently, predictive genetic testing of healthy individuals may soon become a routine component of medical care. How and why is the decision to have a predictive genetic test taken? This article reviews some psychological aspects of predictive genetic-test decisions and discusses the limitations of research to date. A notable limitation is the nontheoretic nature of much of the research. It is argued that theoretical models are needed from which hypotheses about decision making in this context can be derived and tested. Suggestions are offered for future research, and policy implications of research in this area are offered.