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Testing Covariate Effects in Aalen's Linear Hazard Model
Authors:Jon Ketil Grønnesby
Institution:University of Oslo
Abstract:The performance of tests in Aalen's linear regression model is studied using asymptotic power calculations and stochastic simulation. Aalen's original least squares test is compared to two modifications: a weighted least squares test with correct weights and a test where the variance is re-estimated under the null hypothesis. The test with re-estimated variance provides the highest power of the tests for the setting of this paper, and the gain is substantial for covariates following a skewed distribution like the exponential. It is further shown that Aalen's choice for weight function with re-estimated variance is optimal in the one-parameter case against proportional alternatives.
Keywords:Aalen's linear regression model  ordinary least squares  stochastic simulation  survival analysis  weighted least squares
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