Time- and Loading-Dependence in the McKone Model for Dermal Uptake of Organic Chemicals from a Soil Matrix |
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Authors: | David E Burmaster Nancy Irwin Maxwell |
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Institution: | Alceon Corporation, Cambridge, Massachusetts 02238. |
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Abstract: | McKone has recently proposed an innovative two-layer model for dermal uptake of organic chemicals from a soil matrix that explicitly includes variables for properties of the chemical, the soil, the skin, and the exposure. In this note, we investigate the joint time- and loading-dependencies implicit in the model by using MATHEMATICA to find and plot a closed-form function for the uptake fraction for six aromatic hydrocarbons. |
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Keywords: | Dermal exposure soil human skin chemical properties |
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