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Extension of a Two-Stage Conditionally Unbiased Estimator of the Selected Population to the Bivariate Normal Case
Authors:Michael W Sill  Allan R Sampson
Institution:1. The GOG Statistical and Data Center, Roswell Park Cancer Institute , Buffalo, New York, USA;2. Department of Biostatistics , University at Buffalo , Buffalo, New York, USA msill@gogstats.org;4. Department of Statistics , University of Pittsburgh , Pittsburgh, Pennsylvania, USA
Abstract:A useful parameterization of the exponential failure model with imperfect signalling, under random censoring scheme, is considered to accommodate covariates. Simple sufficient conditions for the existence, uniqueness, consistency, and asymptotic normality of maximum likelihood estimators for the parameters in these models are given. The results are then applied to derive the asymptotic properties of the likelihood ratio test for a difference between failure signalling proportions between groups in a ‘one-way’ classification.
Keywords:Biased  Bivariate normal distribution  Clinical trial  Conditional estimation  Correlated observations  Estimation after selection  Maximum  Ranking and selection  Surrogate  UMVUE
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