Repeated measurement analysis for nonnormal data in small samples

The small sample performance of Zeger and Liang's extended generalized linear models for the analysis of longitudinal data (Biometrics, 42,121-130,1986) is investigated for correlated gamma data. Results show that the confidence intervals do not provide desirable coverage of the true parameter due to considerably biased point estimates. Improved estimates are proposed using the jackknife procedure. Simulations performed to evaluate the proposed estimates indicate superior properties to the previous estimates.