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Comparison of Nonparametric and Parametric Methods in Repeated Measures Designs - A Simulation Study
Authors:PK Tandon  ML Moeschberger
Institution:1. Clinical Biostatistics Sterling Research Group , 12144, Rensselaer, NY;2. Department of Preventive Medicine , The Ohio State University , 43210, Columbus, OH, 410 West 10th Avenue
Abstract:This study investigates the performance of parametric and nonparametric tests to analyze repeated measures designs. Both multivariate normal and exponential distributions were simulated for varying values of the correlation and ten or twenty subjects within each cell. For multivariate normal distributions, the type I error rates were lower than the usual 0.05 level for nonparametric tests, whereas the parametric tests without the Greenhouse-Geisser or the Huynh-Feldt adjustment produced slightly higher type I error rates. Type I error rates for nonparametric tests, for multivariate exponential distributions, were more stable than parametric, Greenhouse-Geisser or Huynh-Feldt adjusted tests. For ten subjects within each cell, the parametric tests were more powerful than nonparametric tests. For twenty subjects per cell, the power of the nonparametric and parametric tests was comparable.
Keywords:Repeated measures designs  multivariate normal distribution  Gumbel's bivariate exponential distribution  type I error rates  parametric and nonparametric tests
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