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Bayesian Inference of Odds Ratios in Misclassified Binary Data with a Validation Substudy
Authors:Dewi Rahardja  Yan D Zhao  Hao Helen Zhang
Institution:1. Department of Clinical Sciences and Simmons Cancer Center , UT Southwestern Medical Center , Dallas, Texas, USA rahardja@gmail.com;3. Department of Clinical Sciences and Simmons Cancer Center , UT Southwestern Medical Center , Dallas, Texas, USA;4. Department of Statistics , North Carolina State University , Raleigh, North Carolina, USA
Abstract:We propose a fully Bayesian model with a non-informative prior for analyzing misclassified binary data with a validation substudy. In addition, we derive a closed-form algorithm for drawing all parameters from the posterior distribution and making statistical inference on odds ratios. Our algorithm draws each parameter from a beta distribution, avoids the specification of initial values, and does not have convergence issues. We apply the algorithm to a data set and compare the results with those obtained by other methods. Finally, the performance of our algorithm is assessed using simulation studies.
Keywords:Bayesian inference  Binary data  Credible interval  Misclassification  Odds ratio
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