P-values for two-sided comparisons with a control |
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Authors: | David Bristol |
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Institution: | Schering-Plough Research Institute , 2000 Galloping Hill Road, Kenilworth, NJ, 07033 |
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Abstract: | Critical values for Dunnett's multiple comparison procedure for simultaneously comparing the means of several experimental treatments with the mean of a control treatment are available in many references. However, these values are primarily applicable to one-way analysis of variance with equal sample sizes for the experimental treatments. Even for this design, these critical values do not suffice for situations where the corresponding p-values are desired. Here the technique is presented for calculation of the p-value for multiple comparisons with a control when a general linear model is used for the analysis. A FORTRAN program using IMSL subroutines is described for the calculations. |
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Keywords: | p-values control Dunnett |
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