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The likelihood ratio test foe the homogeneity of the variances in a covariance matrix with block compound symmetry
Authors:Guoyong Jiang  Sanat K. Sarkar
Affiliation:Knoll Pharmaceutical Company , Mount Olive, New Jersey, 07828
Abstract:For the problem of testing the homogeneity of the variances in a covariance matrix with a block compound symmetric structure, the likelihood ratio test is derived in this paper, A modification of the test that allows its distribution to be better approximated by the chi-square distribution is also considered, Formulae for calculating approximate sample size and power are derived, Small sample performances of these tests in the case of two dependent bivariate or trivariate normals are compared to each other and to the competing tests by simulating levels of significance and powers, and recommendation is made of the ones that have good performance, The recommended tests are then demonstrated in an illustrative example.
Keywords:bioavailability  iterative computations  linearly patterned covariance matrices  maximum likelihood estimation  method of scoring: signed log-livelihooD'ratio statistic
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