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Confidence Intervals of Weighted Kappa Coefficient of a Binary Diagnostic Test
Authors:J A Roldán Nofuentes  J D Luna del Castillo  M A Montero Alonso
Institution:1. Biostatistics , School of Medicine, University of Granada , Granada , Spain jaroldan@ugr.es;3. Biostatistics , School of Medicine, University of Granada , Granada , Spain;4. Statistics , School of Social Sciences, Campus of Melilla, University of Granada , Granada , Spain
Abstract:Sensitivity and specificity are classic parameters to assess the performance of a binary diagnostic test. Another useful parameter to measure the performance of a binary test is the weighted kappa coefficient, which is a measure of the classificatory agreement between the binary test and the gold standard. Various confidence intervals are proposed for the weighted kappa coefficient when the binary test and the gold standard are applied to all of the patients in a random sample. The results have been applied to the diagnosis of coronary artery disease.
Keywords:Binary test  Confidence interval  Weighted kappa coefficient
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