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Ranges of Measures of Association for Familial Binary Variables
Authors:N Rao Chaganty  Yihao Deng
Institution:1. Department of Mathematics and Statistics , Old Dominion University , Norfolk, Virginia, USA rchagant@odu.edu;3. Department of Mathematical Sciences , Indiana University Purdue University–Fort Wayne , Fort Wayne, Indiana, USA
Abstract:Familial binary data occur in a wide range of scientific investigations. Numerous measures of association have been proposed in the literature for the study of intra-family dependence of the binary variables. These measures include correlations, odd ratios, kappa statistics, and relative risks. We study the permissible ranges of these measures of association such that a joint distribution exists for the familial binary variables. Our results are useful for developing efficient estimation methods for the measures of association.
Keywords:Familial correlations  GEE  Kappa statistics  Odds ratios  Relative risks
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