Additive Mixed Effect Model for Clustered Doubly Censored Data

Cai and Zeng (2011 Cai, J. and Zeng, D. 2011. Additive mixed effect model for clustered failure time data. Biometrics, 67(4): 1340–1351. Crossref], PubMed] , Google Scholar]) proposed an additive mixed effect model to analyze clustered right-censored data. In this article, we demonstrate that the approach of Cai and Zeng (2011 Cai, J. and Zeng, D. 2011. Additive mixed effect model for clustered failure time data. Biometrics, 67(4): 1340–1351. Crossref], PubMed] , Google Scholar]) can be extended to clustered doubly censored data. Furthermore, when both left- and right-censoring variables are always observed, we propose alternative estimators using the approach of Cai and Cheng (2004 Cai, T. and Cheng, S. C. 2004. Semiparametric regression analysis for doubly censored data. Biometrika, 91: 277–290. Crossref], Web of Science ®] , Google Scholar]). A simulation study is conducted to investigate the performance of the proposed estimators.