Testing for heteroscedasticity of exponential correlation mixed-effects linear models based on M-estimation

Homogeneity of variance is a basic assumption in longitudinal data analysis. However, the assumption is not necessarily appropriate. In this paper, Fisher scoring method is applied to get M-estimator in the exponential correlation mixed-effects linear model. The score tests for heteroscedasticity and correlation coefficient based on M-estimator are then studied. Monte Carlo method is applied to investigate the properties of test statistics. At last, the methods and properties are illustrated by an actual data example.