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A new approach: Interrelated two-way clustering of gene expression data
Authors:B Chandra  S Shanker  Saroj Mishra
Institution:aDepartment of Mathematics, Indian Institute of Technology, Delhi, India;bDepartment of Biochemical Engineering and Biotechnology, Indian Institute of Technology, Delhi, India
Abstract:The paper presents a new approach to interrelated two-way clustering of gene expression data. Clustering of genes has been effected using entropy and a correlation measure, whereas the samples have been clustered using the fuzzy C-means. The efficiency of this approach has been tested on two well known data sets: the colon cancer data set and the leukemia data set. Using this approach, we were able to identify the important co-regulated genes and group the samples efficiently at the same time.
Keywords:Two-way clustering  Microarray data  Gene expression data
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