A new approach: Interrelated two-way clustering of gene expression data |
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Authors: | B. Chandra S. Shanker Saroj Mishra |
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Affiliation: | aDepartment of Mathematics, Indian Institute of Technology, Delhi, India;bDepartment of Biochemical Engineering and Biotechnology, Indian Institute of Technology, Delhi, India |
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Abstract: | The paper presents a new approach to interrelated two-way clustering of gene expression data. Clustering of genes has been effected using entropy and a correlation measure, whereas the samples have been clustered using the fuzzy C-means. The efficiency of this approach has been tested on two well known data sets: the colon cancer data set and the leukemia data set. Using this approach, we were able to identify the important co-regulated genes and group the samples efficiently at the same time. |
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Keywords: | Two-way clustering Microarray data Gene expression data |
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