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ASSESSING THE RELATIONSHIP BETWEEN SYMPTOMS OF ALLERGIC RHINOCONJUNCTIVITIS AND POLLEN COUNTS
Authors:K Byth    DR Cox  P Forder
Institution:NHMRC Clinical Trials Centre;, Westmead Millenium Institute;and Nuffield College
Abstract:The relationship between daily pollen counts during the peak pollen season and hay fever symptoms in known sufferers of pollen allergy was investigated in a Sydney hospital‐based study. This paper develops statistical models for both the short term (day to day) associations and the longer term relationships between these time series. Possible effects of asthma status are investigated. The analyses illustrate how different relationships between time series may be explored in a simple way by working on different time scales with suitably transformed variables.
Keywords:linear mixed effects models  measurement error  multiple time series  surrogate marker
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