A dynamic multistate model of robustness and frailty |
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| Authors: | Robert Schoen Young J Kim |
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| Institution: | 1. Department of Population and Family Health Sciences , Johns Hopkins University , Baltimore, MD, 21205 E-mail: schoen@pop.psu.edu;2. Department of Sociology , Pennsylvania State University , University Park, PA, 16802 |
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| Abstract: | Dynamic multistate models can show realistic population dynamics over time, model complex cycles, and encompass the life history of a cohort. This paper uses a recently developed approach to obtain the analytic solution of a time‐dependent multidimensional differential equation. The illustrative robust/frail model presented shows that the assumption of fixed individual frailty can be abandoned in a two living state model that allows transitions between health statuses and nonproportional hazards of death. |
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| Keywords: | Dynamic multistate frailty Markov heterogeneity closed form |
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