银杏达莫注射液联合弥可保治疗糖尿病周围神经病变的疗效观察

目的研究银杏达莫注射液与弥可保联合应用对糖尿病周围神经病变的治疗效果.方法120例糖尿病周围神经病变患者随机分组对照观察,治疗组60例,给予银杏达莫注射液25m1 生理盐水250ml静脉滴注,每日一次,同时应用弥可保500μg肌肉注射,每日一次,连续应用4周;对照组60例,单用弥可保500μg肌肉注射,每日一次,连续应用4周.分别检测治疗前后的神经传导速度和血液流变学指标.结果治疗组总有效率达86.7%,明显高于对照组的53.3%;运动和感觉神经传导速度有明显提高,且血液流变学指标也有明显改善,两组的差异有显著性.结论银杏达莫注射液与弥可保联合应用可有效缓解糖尿病周围神经病变的症状,提高神经传导速度,降低血粘度,是治疗糖尿病周围神经病变的较好方法.

Study on the Therapeutic Effect of Diabetic Peripheral Neuropathy with Yinxingdamo and Methycobai

Objective To observe the therapeutic effect of diabetic peripheral neuropathy (DPN) with Yinxingdamo and Methycobal.Methods 120 DPN patients were divided randomly into two groups. Therapy group (n = 60) were treated with Yinxingdamo and Methycobal for 4 weeks, control group (n = 60) were only given Methycobal for 4 weeks. Nerve conduction velocity and the blood viscosity were observed before and after treatment. Results Effective rate of treatment for therapy group was 86.7%, it was obviously higher than control group(53.3%). For therapy group, sensory nerve conduction velocity(SNCV) and motor nerve conduction velocity(MNCV) were raised. The values of blood'viscosity were obviously decreased comparing with those in control group.The difference between two groups was significant.Conclusion Therapeutic alliance with Yinxingdamo and Methycobal can relieve DPN symptoms effectively, raise nerve conduction velocity and reduce blood viscosity. Therefore it is a better method for DPN treatment.